McPherson, Ruth

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential: A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

Fruchart, J.-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Després, J.-P., et al. (2019) · Cardiovascular Diabetology

Peroxisome Proliferator-Activated ReceptorsLipoproteins and Cardiovascular Health

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Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N -Oxide, a Proatherogenic Metabolite of Choline and l -Carnitine

Hartiala, J., Bennett, B. J., Tang, W. H. W., Wang, Z., Stewart, A. F. R., Roberts, R., McPherson, R., Lusis, A. J., Hazen, S. L., & Allayee, H. (2014) · Arteriosclerosis, Thrombosis, and Vascular Biology

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

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Factors affecting weight loss variability in obesity

Dent, R., McPherson, R., & Harper, M.-E. (2020) · Metabolism

Pharmacology and Obesity TreatmentBariatric Surgery and Outcomes

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Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

Hartiala, J. A., Wilson Tang, W. H., Wang, Z., Crow, A. L., Stewart, A. F. R., Roberts, R., McPherson, R., Erdmann, J., Willenborg, C., Hazen, S. L., et al. (2016) · Nature Communications

Genetic Associations and EpidemiologyMetabolism and Genetic Disorders

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Decreased Mitochondrial Proton Leak and Reduced Expression of Uncoupling Protein 3 in Skeletal Muscle of Obese Diet-Resistant Women

Harper, M.-E., Dent, R., Monemdjou, S., Bézaire, V., Van Wyck, L., Wells, G., Kavaslar, G. N., Gauthier, A., Tesson, F., & McPherson, R. (2002) · Diabetes

Adipose Tissue and MetabolismMitochondrial Function and Pathology

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A deep catalogue of protein-coding variation in 983,578 individuals

Sun, K. Y., Bai, X., Chen, S., Bao, S., Zhang, C., Kapoor, M., Backman, J., Joseph, T., Maxwell, E., Mitra, G., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

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Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals

Antoun, G., McMurray, F., Thrush, A. B., Patten, D. A., Peixoto, A. C., Slack, R. S., McPherson, R., Dent, R., & Harper, M.-E. (2015) · Diabetologia

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

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IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis

Chen, H.-H., Keyhanian, K., Zhou, X., Vilmundarson, R. O., Almontashiri, N. A. M., Cruz, S. A., Pandey, N. R., Lerma Yap, N., Ho, T., Stewart, C. A., et al. (2015) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

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Genome-wide identification of circulating-miRNA expression quantitative trait loci reveals the role of several miRNAs in the regulation of cardiometabolic phenotypes

Nikpay, M., Beehler, K., Valsesia, A., Hager, J., Harper, M.-E., Dent, R., & McPherson, R. (2019) · Cardiovascular Research

Genetic Associations and EpidemiologyMicroRNA in disease regulation

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Distinct skeletal muscle fiber characteristics and gene expression in diet-sensitive versus diet-resistant obesity

Gerrits, M. F., Ghosh, S., Kavaslar, N., Hill, B., Tour, A., Seifert, E. L., Beauchamp, B., Gorman, S., Stuart, J., Dent, R., et al. (2010) · Journal of Lipid Research

Muscle Physiology and DisordersAdipose Tissue and Metabolism

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Nonstatin Low-Density Lipoprotein–Lowering Therapy and Cardiovascular Risk Reduction—Statement From ATVB Council

Hegele, R. A., Gidding, S. S., Ginsberg, H. N., McPherson, R., Raal, F. J., Rader, D. J., Robinson, J. G., & Welty, F. K. (2015) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

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Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

Lim, E. T., Würtz, P., Havulinna, A. S., Palta, P., Tukiainen, T., Rehnström, K., Esko, T., Mägi, R., Inouye, M., Lappalainen, T., et al. (2014) · PLoS Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

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Redundancy Control in Pathway Databases (ReCiPa): An Application for Improving Gene-Set Enrichment Analysis in Omics Studies and “Big Data” Biology

Vivar, J. C., Pemu, P., McPherson, R., & Ghosh, S. (2013) · OMICS: A Journal of Integrative Biology

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

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High-quality weight loss in obesity: importance of skeletal muscle

Harper, M.-E., Dent, R. R. M., & McPherson, R. (2025) · Diabetes

Nutrition and Health in AgingMuscle Physiology and Disorders

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Targeting skeletal muscle mitochondrial health in obesity

Pileggi, C. A., Hooks, B. G., McPherson, R., Dent, R. R. M., & Harper, M.-E. (2022) · Clinical Science

Adipose Tissue and MetabolismMuscle Physiology and Disorders

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