Natsume, Tohru

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Komatsu, M., Waguri, S., Koike, M., Sou, Y.-S., Ueno, T., Hara, T., Mizushima, N., Iwata, J.-I., Ezaki, J., Murata, S., et al. (2007) · Cell

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,124

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

Hosokawa, N., Hara, T., Kaizuka, T., Kishi, C., Takamura, A., Miura, Y., Iemura, S.-I., Natsume, T., Takehana, K., Yamada, N., et al. (2009) · Molecular Biology of the Cell

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

Cited by 2,076

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

Mizushima, N., Kuma, A., Kobayashi, Y., Yamamoto, A., Matsubae, M., Takao, T., Natsume, T., Ohsumi, Y., & Yoshimori, T. (2003) · Journal of Cell Science

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 791

The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

Jiang, P., Nishimura, T., Sakamaki, Y., Itakura, E., Hatta, T., Natsume, T., & Mizushima, N. (2014) · Molecular Biology of the Cell

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 501

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

Nakada, S., Tai, I., Panier, S., Al-Hakim, A., Iemura, S.-I., Juang, Y.-C., O’Donnell, L., Kumakubo, A., Munro, M., Sicheri, F., et al. (2010) · Nature

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 357

Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.

Kaneko, T., Hamazaki, J., Iemura, S.-I., Sasaki, K., Furuyama, K., Natsume, T., Tanaka, K., & Murata, S. (2009) · Cell

Ubiquitin and proteasome pathwaysHeat shock proteins research

Cited by 211

NARF, an Nemo-like Kinase (NLK)-associated Ring Finger Protein Regulates the Ubiquitylation and Degradation of T Cell Factor/Lymphoid Enhancer Factor (TCF/LEF)

Yamada, M., Ohnishi, J., Ohkawara, B., Iemura, S., Satoh, K., Hyodo-Miura, J., Kawachi, K., Natsume, T., & Shibuya, H. (2006) · Journal of Biological Chemistry

Wnt/β-catenin signaling in development and cancerUbiquitin and proteasome pathways

Cited by 132

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway

Adachi, S., Homoto, M., Tanaka, R., Hioki, Y., Murakami, H., Suga, H., Matsumoto, M., Nakayama, K. I., Hatta, T., Iemura, S.-I., et al. (2014) · Nucleic Acids Research

RNA Research and SplicingCholesterol and Lipid Metabolism

Cited by 109

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFβ-activated kinase 1 for STAT3 Ser-727 phosphorylation

Kojima, H., Sasaki, T., Ishitani, T., Iemura, S.-I., Zhao, H., Kaneko, S., Kunimoto, H., Natsume, T., Matsumoto, K., & Nakajima, K. (2005) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 81

The transmembrane nucleoporin NDC1 is required for targeting of ALADIN to nuclear pore complexes

Yamazumi, Y., Kamiya, A., Nishida, A., Nishihara, A., Iemura, S.-I., Natsume, T., & Akiyama, T. (2009) · Biochemical and Biophysical Research Communications

Nuclear Structure and FunctionDrug Transport and Resistance Mechanisms

Cited by 34

Transplantation of bioengineered liver capable of extended function in a preclinical liver failure model

Higashi, H., Yagi, H., Kuroda, K., Tajima, K., Kojima, H., Nishi, K., Morisaku, T., Hirukawa, K., Fukuda, K., Matsubara, K., et al. (2022) · American Journal of Transplantation

Tissue Engineering and Regenerative Medicine3D Printing in Biomedical Research

Cited by 31