Aderem, Alan

Mechanisms of phagocytosis in macrophages

Aderem, A., & Underhill, D. M. (1999) · Annual Review of Immunology

Phagocytosis and Immune RegulationImmune Response and Inflammation

Cited by 2,854

Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron

Flo, T. H., Smith, K. D., Sato, S., Rodriguez, D. J., Holmes, M. A., Strong, R. K., Akira, S., & Aderem, A. (2004) · Nature

Iron Metabolism and DisordersImmune Response and Inflammation

Cited by 1,877

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

Miao, E. A., Leaf, I. A., Treuting, P. M., Mao, D. P., Dors, M., Sarkar, A., Warren, S. E., Wewers, M. D., & Aderem, A. (2010) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,336

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf

Miao, E. A., Alpuche-Aranda, C. M., Dors, M., Clark, A. E., Bader, M. W., Miller, S. I., & Aderem, A. (2006) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,127

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

Schoggins, J. W., MacDuff, D. A., Imanaka, N., Gainey, M. D., Shrestha, B., Eitson, J. L., Mar, K. B., Richardson, R. B., Ratushny, A. V., Litvak, V., et al. (2014) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 896

Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantation

Bochud, P.-Y., Chien, J. W., Marr, K. A., Leisenring, W. M., Upton, A., Janer, M., Rodrigues, S. D., Li, S., Hansen, J. A., Zhao, L. P., et al. (2008) · New England Journal of Medicine

Antifungal resistance and susceptibilityImmune Response and Inflammation

Cited by 453

The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2

Fischbach, M. A., Lin, H., Zhou, L., Yu, Y., Abergel, R. J., Liu, D. R., Raymond, K. N., Wanner, B. L., Strong, R. K., Walsh, C. T., et al. (2006) · Proceedings of the National Academy of Sciences

Escherichia coli research studiesBacterial Genetics and Biotechnology

Cited by 319

A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages.

Allen, L. H., & Aderem, A. (1995) · The Journal of experimental medicine

Phagocytosis and Immune RegulationCellular transport and secretion

Cited by 296

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

Litvak, V., Ramsey, S. A., Rust, A. G., Zak, D. E., Kennedy, K. A., Lampano, A. E., Nykter, M., Shmulevich, I., & Aderem, A. (2009) · Nature Immunology

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 295

Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion

Shimada, T., Park, B. G., Wolf, A. J., Brikos, C., Goodridge, H. S., Becker, C. A., Reyes, C. N., Miao, E. A., Aderem, A., Götz, F., et al. (2010) · Cell Host & Microbe

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 274

Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli

Cronk, J. C., Derecki, N. C., Ji, E., Xu, Y., Lampano, A. E., Smirnov, I., Baker, W., Norris, G. T., Marin, I., Coddington, N., et al. (2015) · Immunity

Genetics and Neurodevelopmental DisordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 199

Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium

Aachoui, Y., Kajiwara, Y., Leaf, I. A., Mao, D., Ting, J. P.-Y., Coers, J., Aderem, A., Buxbaum, J. D., & Miao, E. A. (2015) · Cell Host & Microbe

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 125

Liver stage malaria infection is controlled by host regulators of lipid peroxidation

Kain, H. S., Glennon, E. K. K., Vijayan, K., Arang, N., Douglass, A. N., Fortin, C. L., Zuck, M., Lewis, A. J., Whiteside, S. L., Dudgeon, D. R., et al. (2020) · Cell Death & Differentiation

Malaria Research and ControlFerroptosis and cancer prognosis

Cited by 91

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Zammit, N. W., Siggs, O. M., Gray, P. E., Horikawa, K., Langley, D. B., Walters, S. N., Daley, S. R., Loetsch, C., Warren, J., Yap, J. Y., et al. (2019) · Nature Immunology

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 80

Path‐seq identifies an essential mycolate remodeling program for mycobacterial host adaptation

Peterson, E. J., Bailo, R., Rothchild, A. C., Arrieta‐Ortiz, M. L., Kaur, A., Pan, M., Mai, D., Abidi, A. A., Cooper, C., Aderem, A., et al. (2019) · Molecular Systems Biology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 63