Lieu, Deborah K.

Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes

Lieu, D. K., Fu, J.-D., Chiamvimonvat, N., Tung, K. C., McNerney, G. P., Huser, T., Keller, G., Kong, C.-W., & Li, R. A. (2013) · Circulation: Arrhythmia and Electrophysiology

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 179

Absence of Transverse Tubules Contributes to Non-Uniform Ca 2+ Wavefronts in Mouse and Human Embryonic Stem Cell–Derived Cardiomyocytes

Lieu, D. K., Liu, J., Siu, C.-W., McNerney, G. P., Tse, H.-F., Abu-Khalil, A., Huser, T., & Li, R. A. (2009) · Stem Cells and Development

Cardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research

Cited by 160

Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives

Chen, A., Lieu, D. K., Freschauf, L., Lew, V., Sharma, H., Wang, J., Nguyen, D., Karakikes, I., Hajjar, R. J., Gopinathan, A., et al. (2011) · Advanced Materials

Cellular Mechanics and InteractionsAdvanced Materials and Mechanics

Cited by 122

Facilitated maturation of Ca 2+ handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression

Liu, J., Lieu, D. K., Siu, C. W., Fu, J.-D., Tse, H.-F., & Li, R. A. (2009) · American Journal of Physiology-Cell Physiology

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 109

Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias

Wang, J., Chen, A., Lieu, D. K., Karakikes, I., Chen, G., Keung, W., Chan, C. W., Hajjar, R. J., Costa, K. D., Khine, M., et al. (2013) · Biomaterials

Cardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research

Cited by 69

Correlation between frataxin expression and contractility revealed by in vitro Friedreich’s ataxia cardiac tissue models engineered from human pluripotent stem cells

Wong, A. O.-T., Wong, G., Shen, M., Chow, M. Z.-Y., Tse, W. W., Gurung, B., Mak, S. Y., Lieu, D. K., Costa, K. D., Chan, C. W., et al. (2019) · Stem Cell Research & Therapy

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 27

Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissues

Cheng, S., Brenière-Letuffe, D., Ahola, V., Wong, A. O. T., Keung, H. Y., Gurung, B., Zheng, Z., Costa, K. D., Lieu, D. K., Keung, W., et al. (2023) · iScience

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 23

Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues

Wong, A. O.-T., Gurung, B., Wong, W. S., Mak, S. Y., Tse, W. W., Li, C. M., Lieu, D. K., Costa, K. D., Li, R. A., & Hajjar, R. J. (2021) · Journal of Molecular and Cellular Cardiology

Cardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research

Cited by 16

Reversal of contractile defects by mediating calcium homeostasis in human mini-heart models of heart failure with preserved ejection fraction (HFpEF) leads to first-in-human gene therapy clinical trial

Costa, K. D., Wong, A. O. T., Mak, S. Y., Roberts, E. G., Keung, W., Correia, C., Walentinsson, A., Christoffersson, J., Cheung, A., Lieu, D. K., et al. (2024) · bioRxiv

Cardiac electrophysiology and arrhythmiasCardiovascular Function and Risk Factors

Cited by 5