Lunnon, Katie

A data-driven approach to preprocessing Illumina 450K methylation array data

Pidsley, R., Y Wong, C. C., Volta, M., Lunnon, K., Mill, J., & Schalkwyk, L. C. (2013) · BMC Genomics

Epigenetics and DNA MethylationGene expression and cancer classification

Cited by 1,143

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

De Jager, P. L., Srivastava, G., Lunnon, K., Burgess, J., Schalkwyk, L. C., Yu, L., Eaton, M. L., Keenan, B. T., Ernst, J., McCabe, C., et al. (2014) · Nature Neuroscience

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 956

Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration

Cunningham, C., Wilcockson, D. C., Campion, S., Lunnon, K., & Perry, V. H. (2005) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsPrion Diseases and Protein Misfolding

Cited by 768

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

Davies, M. N., Volta, M., Pidsley, R., Lunnon, K., Dixit, A., Lovestone, S., Coarfa, C., Harris, R. A., Milosavljevic, A., Troakes, C., et al. (2012) · Genome Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 630

Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease.

Cunningham, C., Campion, S., Lunnon, K., Murray, C. L., Woods, J. F. C., Deacon, R. M. J., Rawlins, J. N. P., & Perry, V. H. (2009) · Biological Psychiatry

Prion Diseases and Protein MisfoldingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 584

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

Lunnon, K., Smith, R., Hannon, E., De Jager, P. L., Srivastava, G., Volta, M., Troakes, C., Al-Sarraj, S., Burrage, J., Macdonald, R., et al. (2014) · Nature Neuroscience

Epigenetics and DNA MethylationAlzheimer's disease research and treatments

Cited by 574

Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

Hannon, E., Lunnon, K., Schalkwyk, L., & Mill, J. (2015) · Epigenetics

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 455

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

Thambisetty, M., Simmons, A., Velayudhan, L., Hye, A., Campbell, J., Zhang, Y., Wahlund, L.-O., Westman, E., Kinsey, A., Güntert, A., et al. (2010) · Archives of General Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 405

A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex

Marzi, S. J., Leung, S. K., Ribarska, T., Hannon, E., Smith, A. R., Pishva, E., Poschmann, J., Moore, K., Troakes, C., Al-Sarraj, S., et al. (2018) · Nature Neuroscience

Alzheimer's disease research and treatmentsGenomics and Chromatin Dynamics

Cited by 232

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway

Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., Lourdusamy, A., Furney, S., et al. (2014) · Molecular Psychiatry

Alzheimer's disease research and treatmentsClusterin in disease pathology

Cited by 222

Mitochondrial genes are altered in blood early in Alzheimer's disease

Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., et al. (2017) · Neurobiology of Aging

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 190

Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

Smith, R. G., Hannon, E., De Jager, P. L., Chibnik, L., Lott, S. J., Condliffe, D., Smith, A. R., Haroutunian, V., Troakes, C., Al‐Sarraj, S., et al. (2018) · Alzheimer's & Dementia

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 184

Inflammatory Proteins in Plasma Are Associated with Severity of Alzheimer’s Disease

Leung, R., Proitsi, P., Simmons, A., Lunnon, K., Güntert, A., Kronenberg, D., Pritchard, M., Tsolaki, M., Mecocci, P., Kloszewska, I., et al. (2013) · PLoS ONE

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 160

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer’s disease

Furney, S. J., Simmons, A., Breen, G., Pedroso, I., Lunnon, K., Proitsi, P., Hodges, A., Powell, J., Wahlund, L.-O., Kloszewska, I., et al. (2011) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 157

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

Rutten, B. P. F., Vermetten, E., Vinkers, C. H., Ursini, G., Daskalakis, N. P., Pishva, E., de Nijs, L., Houtepen, L. C., Eijssen, L., Jaffe, A. E., et al. (2018) · Molecular Psychiatry

Posttraumatic Stress Disorder ResearchEpigenetics and DNA Methylation

Cited by 142

Systemic Inflammation Modulates Fc Receptor Expression on Microglia during Chronic Neurodegeneration

Lunnon, K., Teeling, J. L., Tutt, A. L., Cragg, M. S., Glennie, M. J., & Perry, V. H. (2011) · The Journal of Immunology

Neuroinflammation and Neurodegeneration MechanismsPrion Diseases and Protein Misfolding

Cited by 138

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

Condliffe, D., Wong, A., Troakes, C., Proitsi, P., Patel, Y., Chouliaras, L., Fernandes, C., Cooper, J., Lovestone, S., Schalkwyk, L., et al. (2014) · Neurobiology of Aging

Epigenetics and DNA MethylationAlzheimer's disease research and treatments

Cited by 131

Plasma Based Markers of [11C] PiB-PET Brain Amyloid Burden

Kiddle, S. J., Thambisetty, M., Simmons, A., Riddoch-Contreras, J., Hye, A., Westman, E., Pike, I., Ward, M., Johnston, C., Lupton, M. K., et al. (2012) · PLoS ONE

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 100

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

study, T. A. I. B. A. L., Nabais, M. F., Initiative, T. A. D. N., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., Kwok, J. B., Mather, K. A., et al. (2021) · Genome Biology

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 99

An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

Roubroeks, J. A. Y., Smith, A. R., Smith, R. G., Pishva, E., Ibrahim, Z., Sattlecker, M., Hannon, E. J., Kłoszewska, I., Mecocci, P., Soininen, H., et al. (2020) · Neurobiology of Aging

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 82

Epigenetic studies in Alzheimer's disease: Current findings, caveats, and considerations for future studies

Lunnon, K., & Mill, J. (2013) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 78

Transcriptional signatures of tau and amyloid neuropathology

Castanho, I., Murray, T. K., Hannon, E., Jeffries, A., Walker, E., Laing, E., Baulf, H., Harvey, J., Bradshaw, L., Randall, A., et al. (2020) · Cell Reports

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 62

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

Proitsi, P., Lee, S. H., Lunnon, K., Keohane, A., Powell, J., Troakes, C., Al-Sarraj, S., Furney, S., Soininen, H., Kłoszewska, I., et al. (2014) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57