Tschaharganeh, Darjus F.

Non-Cell-Autonomous Tumor Suppression by p53

Lujambio, A., Akkari, L., Simon, J., Grace, D., Tschaharganeh, D. F., Bolden, J. E., Zhao, Z., Thapar, V., Joyce, J. A., Krizhanovsky, V., et al. (2013) · Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 766

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

Weissmueller, S., Manchado, E., Saborowski, M., Morris, J. P., Wagenblast, E., Davis, C. A., Moon, S.-H., Pfister, N. T., Tschaharganeh, D. F., Kitzing, T., et al. (2014) · Cell

Cancer-related Molecular PathwaysPancreatic and Hepatic Oncology Research

Cited by 466

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

Tasdemir, N., Banito, A., Roe, J.-S., Alonso-Curbelo, D., Camiolo, M., Tschaharganeh, D. F., Huang, C.-H., Aksoy, O., Bolden, J. E., Chen, C.-C., et al. (2016) · Cancer Discovery

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 415

Optimized base editors enable efficient editing in cells, organoids and mice

Zafra, M. P., Schatoff, E. M., Katti, A., Foronda, M., Breinig, M., Schweitzer, A. Y., Simon, A., Han, T., Goswami, S., Montgomery, E., et al. (2018) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 347

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

Tschaharganeh, D. F., Chen, X., Latzko, P., Malz, M., Gaida, M. M., Felix, K., Ladu, S., Singer, S., Pinna, F., Gretz, N., et al. (2013) · Gastroenterology

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

Cited by 326

p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer

Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., et al. (2014) · Cell

Cancer-related Molecular PathwaysLiver physiology and pathology

Cited by 227

GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile

Rusu, P., Shao, C., Neuerburg, A., Acikgöz, A. A., Wu, Y., Zou, P., Phapale, P., Shankar, T. S., Döring, K., Dettling, S., et al. (2019) · Cell Stem Cell

Glioma Diagnosis and TreatmentCancer Cells and Metastasis

Cited by 108

Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness

Wan, S., Meyer, A., Weiler, S. M. E., Rupp, C., Tóth, M., Sticht, C., Singer, S., Thomann, S., Roessler, S., Schorpp‐Kistner, M., et al. (2018) · Hepatology

Hepatocellular Carcinoma Treatment and PrognosisHippo pathway signaling and YAP/TAZ

Cited by 79

Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice

Kroy, D. C., Beraza, N., Tschaharganeh, D. F., Sander, L. E., Erschfeld, S., Giebeler, A., Liedtke, C., Wasmuth, H. E., Trautwein, C., & Streetz, K. L. (2010) · Hepatology

Cytokine Signaling Pathways and InteractionsLiver Disease Diagnosis and Treatment

Cited by 76

Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis

Lim, B., Kamal, A., Gomez Ramos, B., Adrian Segarra, J. M., Ibarra, I. L., Dignas, L., Kindinger, T., Volz, K., Rahbari, M., Rahbari, N., et al. (2025) · Nature Genetics

Liver physiology and pathologyPluripotent Stem Cells Research

Cited by 17

Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumourigenesis

Lim, B., Kamal, A., Gomez Ramos, B., Adrian Segarra, J., Ibarra, I., Dignas, L., Kindinger, T., Volz, K., Rahbari, M., Rahbari, N., et al. (2024) · Nature Genetics

Liver physiology and pathologyPluripotent Stem Cells Research

Cited by 17