Tam, Ying K.

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques

Pardi, N., LaBranche, C. C., Ferrari, G., Cain, D. W., Tombácz, I., Parks, R. J., Muramatsu, H., Mui, B. L., Tam, Y. K., Karikó, K., et al. (2019) · Molecular Therapy - Nucleic Acids

HIV Research and TreatmentSARS-CoV-2 and COVID-19 Research

Cited by 103

Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets

Conway, A., Mendel, M., Kim, K., McGovern, K., Boyko, A., Zhang, L., Miller, J. C., DeKelver, R. C., Paschon, D. E., Mui, B. L., et al. (2019) · Molecular Therapy

RNA Interference and Gene DeliveryCRISPR and Genetic Engineering

Cited by 95

Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria

Raj, D. K., Das Mohapatra, A., Jnawali, A., Zuromski, J., Jha, A., Cham-Kpu, G., Sherman, B., Rudlaff, R. M., Nixon, C. E., Hilton, N., et al. (2020) · Nature

Malaria Research and ControlBlood groups and transfusion

Cited by 93

Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin

Huysmans, H., Zhong, Z., De Temmerman, J., Mui, B. L., Tam, Y. K., Mc Cafferty, S., Gitsels, A., Vanrompay, D., & Sanders, N. N. (2019) · Molecular Therapy - Nucleic Acids

RNA Interference and Gene DeliveryAdvancements in Transdermal Drug Delivery

Cited by 83

mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model

Sittplangkoon, C., Alameh, M.-G., Weissman, D., Lin, P. J. C., Tam, Y. K., Prompetchara, E., & Palaga, T. (2022) · Frontiers in Immunology

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 79

Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice

Willis, E., Pardi, N., Parkhouse, K., Mui, B. L., Tam, Y. K., Weissman, D., & Hensley, S. E. (2020) · Science Translational Medicine

Influenza Virus Research StudiesImmunotherapy and Immune Responses

Cited by 54

Pieter Cullis’ quest for a lipid-based, fusogenic delivery system for nucleic acid therapeutics: success with siRNA so what about mRNA?

Tam, Y. K., Madden, T. D., & Hope, M. J. (2016) · Journal of Drug Targeting

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 20

Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice

Smith, A. R., Rizvi, F., Everton, E., Adeagbo, A., Wu, S., Tam, Y., Muramatsu, H., Pardi, N., Weissman, D., & Gouon-Evans, V. (2024) · Nature Communications

Liver physiology and pathologyRNA Interference and Gene Delivery

Cited by 18