Bikard, David

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

Jiang, W., Bikard, D., Cox, D., Zhang, F., & Marraffini, L. A. (2013) · Nature Biotechnology

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 2,429

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

Bikard, D., Euler, C. W., Jiang, W., Nussenzweig, P. M., Goldberg, G. W., Duportet, X., Fischetti, V. A., & Marraffini, L. A. (2014) · Nature Biotechnology

CRISPR and Genetic EngineeringBacteriophages and microbial interactions

Cited by 986

Conjugative DNA Transfer Induces the Bacterial SOS Response and Promotes Antibiotic Resistance Development through Integron Activation

Baharoglu, Z., Bikard, D., & Mazel, D. (2010) · PLoS Genetics

Bacterial Genetics and BiotechnologyAntibiotic Resistance in Bacteria

Cited by 319

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

Rostain, W., Grebert, T., Vyhovskyi, D., Pizarro, P. T., Tshinsele-Van Bellingen, G., Cui, L., & Bikard, D. (2023) · Nucleic Acids Research

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 85

Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment

Malbranke, C., Rostain, W., Depardieu, F., Cocco, S., Monasson, R., & Bikard, D. (2023) · PLoS Computational Biology

Protein Structure and DynamicsCRISPR and Genetic Engineering

Cited by 15

Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment

Malbranke, C., Rostain, W., Depardieu, F., Cocco, S., Monasson, R., & Bikard, D. (2023) · PLOS Computational Biology

Protein Structure and DynamicsCRISPR and Genetic Engineering

Cited by 15