Sargent, Michelle A.

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart

Fu, X., Khalil, H., Kanisicak, O., Boyer, J. G., Vagnozzi, R. J., Maliken, B. D., Sargent, M. A., Prasad, V., Valiente-Alandi, I., Blaxall, B. C., et al. (2018) · Journal of Clinical Investigation

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 636

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

Karch, J., Kwong, J. Q., Burr, A. R., Sargent, M. A., Elrod, J. W., Peixoto, P. M., Martinez-Caballero, S., Osinska, H., Cheng, E. H.-Y., Robbins, J., et al. (2013) · eLife

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 290

Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD

Karch, J., Bround, M. J., Khalil, H., Sargent, M. A., Latchman, N., Terada, N., Peixoto, P. M., & Molkentin, J. D. (2019) · Science Advances

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 250

Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure

Heineke, J., Auger-Messier, M., Xu, J., Sargent, M., York, A., Welle, S., & Molkentin, J. D. (2010) · Circulation

Muscle Physiology and DisordersCardiac Fibrosis and Remodeling

Cited by 238

Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy

Kwong, J. Q., Davis, J., Baines, C. P., Sargent, M. A., Karch, J., Wang, X., Huang, T., & Molkentin, J. D. (2014) · Cell Death & Differentiation

Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion

Cited by 174

Autophagic cell death is dependent on lysosomal membrane permeability through bax and bak

Karch, J., Schips, T. G., Maliken, B. D., Brody, M. J., Sargent, M. A., Kanisicak, O., & Molkentin, J. D. (2017) · eLife

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 91

Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart

Liu, R., Khalil, H., Lin, S.-C. J., Sargent, M. A., York, A. J., & Molkentin, J. D. (2016) · PLOS ONE

Cardiac Fibrosis and RemodelingSignaling Pathways in Disease

Cited by 10