Abdelmohsen, Kotb

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model

Zhang, P., Kishimoto, Y., Grammatikakis, I., Gottimukkala, K., Cutler, R. G., Zhang, S., Abdelmohsen, K., Bohr, V. A., Misra Sen, J., Gorospe, M., et al. (2019) · Nature Neuroscience

Alzheimer's disease research and treatmentsTelomeres, Telomerase, and Senescence

Cited by 977

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

Abdelmohsen, K., Panda, A. C., Munk, R., Grammatikakis, I., Dudekula, D. B., De, S., Kim, J., Noh, J. H., Kim, K. M., Martindale, J. L., et al. (2017) · RNA Biology

Circular RNAs in diseasesRNA Research and Splicing

Cited by 858

Transcriptome signature of cellular senescence

Casella, G., Munk, R., Kim, K. M., Piao, Y., De, S., Abdelmohsen, K., & Gorospe, M. (2019) · Nucleic Acids Research

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 359

microRNA Expression Patterns Reveal Differential Expression of Target Genes with Age

Noren Hooten, N., Abdelmohsen, K., Gorospe, M., Ejiogu, N., Zonderman, A. B., & Evans, M. K. (2010) · PLoS ONE

MicroRNA in disease regulationGenetics, Aging, and Longevity in Model Organisms

Cited by 357

Identification of senescent cell surface targetable protein DPP4

Kim, K. M., Noh, J. H., Bodogai, M., Martindale, J. L., Yang, X., Indig, F. E., Basu, S. K., Ohnuma, K., Morimoto, C., Johnson, P. F., et al. (2017) · Genes & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 270

p16INK4a Translation Suppressed by miR-24

Lal, A., Kim, H. H., Abdelmohsen, K., Kuwano, Y., Pullmann, R., Srikantan, S., Subrahmanyam, R., Martindale, J. L., Yang, X., Ahmed, F., et al. (2008) · PLoS ONE

MicroRNA in disease regulationTelomeres, Telomerase, and Senescence

Cited by 268

Evidence for miR‐181 involvement in neuroinflammatory responses of astrocytes

Hutchison, E. R., Kawamoto, E. M., Taub, D. D., Lal, A., Abdelmohsen, K., Zhang, Y., Wood, W. H., Lehrmann, E., Camandola, S., Becker, K. G., et al. (2013) · Glia

Neuroinflammation and Neurodegeneration MechanismsMicroRNA in disease regulation

Cited by 246

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

Abdelmohsen, K., Srikantan, S., Kuwano, Y., & Gorospe, M. (2008) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationRNA Research and Splicing

Cited by 230

Analysis of Turnover and Translation Regulatory RNA-Binding Protein Expression through Binding to Cognate mRNAs

Pullmann, R., Kim, H. H., Abdelmohsen, K., Lal, A., Martindale, J. L., Yang, X., & Gorospe, M. (2007) · Molecular and Cellular Biology

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 199

Survey of senescent cell markers with age in human tissues

Idda, M. L., McClusky, W. G., Lodde, V., Munk, R., Abdelmohsen, K., Rossi, M., & Gorospe, M. (2020) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 188

miR-375 Inhibits Differentiation of Neurites by Lowering HuD Levels

Abdelmohsen, K., Hutchison, E. R., Lee, E. K., Kuwano, Y., Kim, M. M., Masuda, K., Srikantan, S., Subaran, S. S., Marasa, B. S., Mattson, M. P., et al. (2010) · Molecular and Cellular Biology

MicroRNA in disease regulationNeurogenesis and neuroplasticity mechanisms

Cited by 134

SASP regulation by noncoding RNA

Panda, A. C., Abdelmohsen, K., & Gorospe, M. (2017) · Mechanisms of Ageing and Development

Telomeres, Telomerase, and SenescenceCancer-related molecular mechanisms research

Cited by 86

Transcriptome signature of cellular senescence

Casella, G., Munk, R., Kim, K. M., Piao, Y., De, S., Abdelmohsen, K., & Gorospe, M. (2019) · Nucleic Acids Research

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 83

The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress

Anerillas, C., Mazan-Mamczarz, K., Herman, A. B., Munk, R., Lam, K.-W. G., Calvo-Rubio, M., Garrido, A., Tsitsipatis, D., Martindale, J. L., Altés, G., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceHippo pathway signaling and YAP/TAZ

Cited by 76

Early SRC activation skews cell fate from apoptosis to senescence

Anerillas, C., Herman, A. B., Rossi, M., Munk, R., Lehrmann, E., Martindale, J. L., Cui, C.-Y., Abdelmohsen, K., De, S., & Gorospe, M. (2022) · Science Advances

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 71

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice

Herman, A. B., Tsitsipatis, D., Anerillas, C., Mazan-Mamczarz, K., Carr, A. E., Gregg, J. M., Wang, M., Zhang, J., Michel, M., Henry-Smith, C. A., et al. (2023) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases

Cited by 50

NF90 coordinately represses the senescence-associated secretory phenotype

Tominaga-Yamanaka, K., Abdelmohsen, K., Martindale, J. L., Yang, X., Taub, D. D., & Gorospe, M. (2012) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 49

A BDNF-TrkB autocrine loop enhances senescent cell viability

Anerillas, C., Herman, A. B., Munk, R., Garrido, A., Lam, K.-W. G., Payea, M. J., Rossi, M., Tsitsipatis, D., Martindale, J. L., Piao, Y., et al. (2022) · Nature Communications

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 35

Reduced endosomal microautophagy activity in aging associates with enhanced exocyst‐mediated protein secretion

Krause, G. J., Diaz, A., Jafari, M., Khawaja, R. R., Agullo‐Pascual, E., Santiago‐Fernández, O., Richards, A. L., Chen, K., Dmitriev, P., Sun, Y., et al. (2022) · Aging Cell

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 35

Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis

Herman, A. B., Anerillas, C., Harris, S. C., Munk, R., Martindale, J. L., Yang, X., Mazan-Mamczarz, K., Zhang, Y., Heckenbach, I. J., Scheibye-Knudsen, M., et al. (2021) · Nucleic Acids Research

Telomeres, Telomerase, and SenescenceMicroRNA in disease regulation

Cited by 31

SenCat: Cataloging human cell senescence through multi-omic profiling of multiple senescent primary cell types

Anerillas, C., Altés, G., Gresova, K., Tsitsipatis, D., Mazan-Mamczarz, K., Banarjee, R., Cunningham, A. S. G., Salamini-Montemurri, M., Yang, J.-H., Munk, R., et al. (2026) · Molecular Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 11