Armstrong, Lyle

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

Volpato, V., Smith, J., Sandor, C., Ried, J. S., Baud, A., Handel, A., Newey, S. E., Wessely, F., Attar, M., Whiteley, E., et al. (2018) · Stem Cell Reports

Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics

Cited by 165

Overexpression of Telomerase Confers Growth Advantage, Stress Resistance, and Enhanced Differentiation of ESCs Toward the Hematopoietic Lineage

Armstrong, L., Saretzki, G., Peters, H., Wappler, I., Evans, J., Hole, N., von Zglinicki, T., & Lako, M. (2005) · Stem Cells

Telomeres, Telomerase, and SenescencePluripotent Stem Cells Research

Cited by 153

A Key Role for Telomerase Reverse Transcriptase Unit in Modulating Human Embryonic Stem Cell Proliferation, Cell Cycle Dynamics, and In Vitro Differentiation

Yang, C., Przyborski, S., Cooke, M. J., Zhang, X., Stewart, R., Anyfantis, G., Atkinson, S. P., Saretzki, G., Armstrong, L., & Lako, M. (2008) · Stem Cells

Telomeres, Telomerase, and SenescencePluripotent Stem Cells Research

Cited by 136

An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure

Hallam, D., Collin, J., Bojic, S., Chichagova, V., Buskin, A., Xu, Y., Lafage, L., Otten, E. G., Anyfantis, G., Mellough, C., et al. (2017) · Stem Cells

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 75

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

Jiang, Y., Cowley, S. A., Siler, U., Melguizo, D., Tilgner, K., Browne, C., Dewilton, A., Przyborski, S., Saretzki, G., James, W. S., et al. (2012) · Stem Cells

Pluripotent Stem Cells ResearchImmunodeficiency and Autoimmune Disorders

Cited by 71

Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function

Cerniauskas, E., Kurzawa-Akanbi, M., Xie, L., Hallam, D., Moya-Molina, M., White, K., Steel, D., Doherty, M., Whitfield, P., Al-Aama, J., et al. (2020) · Stem Cells Translational Medicine

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 58

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- and method-dependent

Chichagova, V., Hilgen, G., Ghareeb, A., Georgiou, M., Carter, M., Sernagor, E., Lako, M., & Armstrong, L. (2020) · Stem Cells

Retinal Development and DisordersPluripotent Stem Cells Research

Cited by 58

Deciphering the Impact of PROM1 Alternative Splicing on Human Photoreceptor Development and Maturation

Lako, M., Molina, M. M., Dorgau, B., Flood, E., Letteboer, S., Lorentzen, E., Coxhead, J., Smith, G., Roepman, R., Nagaraja-Grellscheid, S., et al. (2024) · Cell Death and Disease

Retinal Development and DisordersRNA Research and Splicing

Cited by 11