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Transforming Growth Factor β Suppresses Human Telomerase Reverse Transcriptase (hTERT) by Smad3 Interactions with c-Myc and the hTERT Gene

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Identification of Oxygen-Sensitive Transcriptional Programs in Human Embryonic Stem Cells

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Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing

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Non-canonical Roles of Telomerase: Unraveling the Imbroglio

Ségal-Bendirdjian, E., & Géli, V. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00332 · Cited by 101 · see citing works

Transplantation of Mesenchymal Cells Rejuvenated by the Overexpression of Telomerase and Myocardin Promotes Revascularization and Tissue Repair in a Murine Model of Hindlimb Ischemia

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Telomere Shortening and Oxidative Stress in Aged Macrophages Results in Impaired STAT5a Phosphorylation

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Krüppel-Like Transcription Factor 4 Contributes to Maintenance of Telomerase Activity in Stem Cells

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Telomere Protection Mechanisms Change during Neurogenesis and Neuronal Maturation: Newly Generated Neurons Are Hypersensitive to Telomere and DNA Damage

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Dyrk2-associated EDD-DDB1-VprBP E3 Ligase Inhibits Telomerase by TERT Degradation

Jung, H., Wang, X., Jun, S., & Park, J. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.416792 · Cited by 72 · see citing works

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

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Telomere regulation in pluripotent stem cells

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The beginning of GPX2 and 30 years later

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Telomere Length Maintenance, Shortening, and Lengthening

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The Emerging Roles for Telomerase in the Central Nervous System

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Telomeres, senescence, and hematopoietic stem cells

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The Role of Mitochondria in Stem Cell Biology

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Mechanisms of self-renewal in human embryonic stem cells

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PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells

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A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis

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Embryonic Stem Cell-Derived Neurons Form Functional Networks In Vitro

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The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems

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Global gene expression response to telomerase in bovine adrenocortical cells

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Telomerase-mediated telomere elongation from human blastocysts to embryonic stem cells

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Mitochondrial Dysfunction and Cell Senescence: Cause or Consequence?

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Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells

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Predicting attention-deficit/hyperactivity disorder severity from psychosocial stress and stress-response genes: a random forest regression approach

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HIV-1 Vpr Protein Inhibits Telomerase Activity via the EDD-DDB1-VPRBP E3 Ligase Complex

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Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas

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Experimental manipulation of telomere length: does it reveal a corner-stone role for telomerase in the natural variability of individual fitness?

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Multiple Involvement of Oxidative Stress in Werner Syndrome Phenotype

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G-Quadruplexes as Potential Therapeutic Targets for Embryonal Tumors

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Mechanisms of Action of TGF‐β in Cancer

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Potential of Naturally Derived Compounds in Telomerase and Telomere Modulation in Skin Senescence and Aging

Jacczak, B., Rubiś, B., & Totoń, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126381 · Cited by 41 · see citing works

TGF-β and cancer: Is Smad3 a repressor of hTERT gene?

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Telomerase as a “stemness” enzyme

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New dimeric carbazole–benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer

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Telomeres and Telomerase in Stem Cells during Aging and Disease

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Interleukin-8 prevents oxidative stress-induced human endothelial cell senescence via telomerase activation

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The Genomic Health of Human Pluripotent Stem Cells: Genomic Instability and the Consequences on Nuclear Organization

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Deficiency of telomerase activity aggravates the blood–brain barrier disruption and neuroinflammatory responses in a model of experimental stroke

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Research Advancements in Porcine Derived Mesenchymal Stem Cells

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Human telomerase represses ROS-dependent cellular responses to Tumor Necrosis Factor-α without affecting NF-κB activation

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Microenvironmental Regulation of Telomerase Isoforms in Human Embryonic Stem Cells

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Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase

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Telomerase: not just for the elongation of telomeres

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Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells

Henriksen, J. M., Stabell, M., Meza‐Zepeda, L. A., Lauvrak, S. U., Kassem, M. S., & Myklebost, O. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-329 · Cited by 32 · see citing works

Structural Dynamics of Lateral and Diagonal Loops of Human Telomeric G-Quadruplexes in Extended MD Simulations

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Species-Specific Telomere Length Differences Between Blastocyst Cell Compartments and Ectopic Telomere Extension in Early Bovine Embryos by Human Telomerase Reverse Transcriptase

Iqbal, K., Kues, W. A., Baulain, U., Garrels, W., Herrmann, D., & Niemann, H. J. (2010) · Biology of Reproduction · doi:10.1095/biolreprod.110.087205 · Cited by 30 · see citing works

Clonal Hematopoiesis in Aging

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Telomerase: The Devil Inside

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Silencing of the Expression of Pluripotent Driven-Reporter Genes Stably Transfected into Human Pluripotent Cells

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Transcriptional and functional differences in stem cell populations isolated from extraocular and limb muscles

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Differentiation Capacity of Human Urine-Derived Stem Cells to Retain Telomerase Activity

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Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase

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The role of telomere-binding modulators in pluripotent stem cells

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TGF-β induces telomerase-dependent pancreatic tumor cell cycle arrest

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Stem cells, DNA damage, ageing and cancer.

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Telomeres and Tissue Engineering: The Potential Roles of TERT in VEGF-mediated Angiogenesis

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The Telomerase Complex Directly Controls Hematopoietic Stem Cell Differentiation and Senescence in an Induced Pluripotent Stem Cell Model of Telomeropathy

Jose, S. S., Tidu, F., Búřilová, P., Kepák, T., Bendíčková, K., & Frič, J. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00345 · Cited by 23 · see citing works

Electromagnetic Fields and Stem Cell Fate: When Physics Meets Biology

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Telomere length is regulated by FGF-2 in human embryonic stem cells and affects the life span of its differentiated progenies

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Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases

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Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells

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Transplantation of telomerase/myocardin-co-expressing mesenchymal cells in the mouse promotes myocardial revascularization and tissue repair

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Immortalization of Neural Precursors When Telomerase Is Overexpressed in Embryonal Carcinomas and Stem Cells

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Regulation of Telomerase Activity by Interferon Regulatory Factors 4 and 8 in Immune Cells

Hrdličková, R., Nehyba, J., & Bose, H. R. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00961-08 · Cited by 20 · see citing works

Telomere Biology in Stem Cells and Reprogramming

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Telomere Maintenance as Therapeutic Target in Embryonal Tumours

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Telomerase immortalization of principal cells from mouse collecting duct

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Recent technological advancements in stem cell research for targeted therapeutics

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Inadvertent presence of pluripotent cells in monolayers derived from differentiated embryoid bodies

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Enhanced self-renewal of human pluripotent stem cells by simulated microgravity

Timilsina, S., Kirsch-Mangu, T. K., Werth, S., Shepard, B. D., Ma, T., & Villa-Diaz, L. G. (2022) · npj Microgravity · doi:10.1038/s41526-022-00209-4 · Cited by 16 · see citing works

Role of Mesenchymal Stem/Stromal Cells (MSCs) and MSC-Derived Extracellular Vesicles (EVs) in Prevention of Telomere Length Shortening, Cellular Senescence, and Accelerated Biological Aging

Arellano, M. G., VanHeest, M., Emmadi, S., Abdul‐Hafez, A., Ibrahim, S. A. E.-F., Thiruvenkataramani, R. P., Teleb, R. S., Omar, H., Kesaraju, T., Mohamed, T., et al. (2024) · Bioengineering · doi:10.3390/bioengineering11060524 · Cited by 15 · see citing works

Leishmania major Telomerase TERT Protein Has a Nuclear/Mitochondrial Eclipsed Distribution That Is Affected by Oxidative Stress

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Immortalization and Characterization of Porcine Ventricular Endocardial Endothelial Cells

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Regeneration in pig livers by compensatory hyperplasia induces high levels of telomerase activity

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Variation of Telomerase Activity and Morphology in Porcine Mesenchymal Stem Cells and Fibroblasts during Prolonged in vitro Culture

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Proteome alteration induced by hTERT transfection of human fibroblast cells

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Search for naïve human pluripotent stem cells

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Telomerase dynamics in stem cells: Unraveling the molecular nexus of cellular aging and regeneration

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Stable Phenotype and Function of Immortalized Lin − Sca-1 + Cardiac Progenitor Cells in Long-Term Culture: A Step Closer to Standardization

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The Role of Mitochondria in Stem Cell Biology

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Quantitative proteomic analysis of human breast epithelial cells with differential telomere length

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In Vitro Developmental Potential of Nuclear Transfer Embryos Cloned with Enucleation Methods using Pre‐denuded Bovine Oocytes

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A Key Role for Telomerase Reverse Transcriptase Unit in Modulating Human Embryonic Stem Cell Proliferation, Cell Cycle Dynamics, and In Vitro Differentiation

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Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis

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