Miller, Walter L.

Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein

Bose, M., Whittal, R. M., Miller, W. L., & Bose, H. S. (2008) · Journal of Biological Chemistry

Mitochondrial Function and PathologyAdrenal Hormones and Disorders

Cited by 143

Congenital adrenal hyperplasia due to deficient cholesterol side-chain cleavage activity (20,22 desmolase) in a patient treated for 18 years

HAUFFA, B. P., MILLER, W. L., GRUMBACH, M. M., CONTE, F. A., & KAPLAN, S. L. (1985) · Clinical Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 141

Construction and function of fusion enzymes of the human cytochrome P450scc system

HARIKRISHNA, J. A., BLACK, S. M., SZKLARZ, G. D., & MILLER, W. L. (1993) · DNA and Cell Biology

Steroid Chemistry and BiochemistryMetal-Catalyzed Oxygenation Mechanisms

Cited by 141

Human adrenodoxin: cloning of three cDNAs and cycloheximide enhancement in JEG-3 cells

Picado-Leonard, J., Voutilainen, R., Kao, L. C., Chung, B. C., Strauss, J. F., & Miller, W. L. (1988) · Journal of Biological Chemistry

Mitochondrial Function and PathologyMetalloenzymes and iron-sulfur proteins

Cited by 140

Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc

Kim, C. J., Lin, L., Huang, N., Quigley, C. A., AvRuskin, T. W., Achermann, J. C., & Miller, W. L. (2008) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 139

Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17

Pandey, A. V., Mellon, S. H., & Miller, W. L. (2003) · Journal of Biological Chemistry

Adrenal Hormones and DisordersHormonal Regulation and Hypertension

Cited by 137

Missense mutation serine106—-proline causes 17 alpha-hydroxylase deficiency

Lin, D., Harikrishna, J. A., Moore, C. C., Jones, K. L., & Miller, W. L. (1991) · Journal of Biological Chemistry

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 135

Rearrangements and point mutations of P450c21 genes are distinguished by five restriction endonuclease haplotypes identified by a new probing strategy in 57 families with congenital adrenal hyperplasia

Morel, Y., André, J., Uring-Lambert, B., Hauptmann, G., Bétuel, H., Tossi, M., Forest, M. G., David, M., Bertrand, J., & Miller, W. L. (1989) · Journal of Clinical Investigation

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 134

The mitochondrial environment is required for activity of the cholesterol side-chain cleavage enzyme, cytochrome P450scc

Black, S. M., Harikrishna, J. A., Szklarz, G. D., & Miller, W. L. (1994) · Proceedings of the National Academy of Sciences

Steroid Chemistry and BiochemistryAdrenal Hormones and Disorders

Cited by 133

Mutations in the Steroidogenic Acute Regulatory Protein (StAR) in Six Patients with Congenital Lipoid Adrenal Hyperplasia1

Bose, H. S., Sato, S., Aisenberg, J., Shalev, S. A., Matsuo, N., & Miller, W. L. (2000) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 131

Considering Sex as a Biological Variable in Basic and Clinical Studies: An Endocrine Society Scientific Statement

Bhargava, A., Arnold, A. P., Bangasser, D. A., Denton, K. M., Gupta, A., Hilliard Krause, L. M., Mayer, E. A., McCarthy, M., Miller, W. L., Raznahan, A., et al. (2021) · Endocrine Reviews

Sex and Gender in HealthcareSexual Differentiation and Disorders

Cited by 130

Androgen synthesis in adrenarche

Miller, W. L. (2009) · Reviews in Endocrine and Metabolic Disorders

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 127

THE MOLECULAR GENETICS OF 21-HYDROXYLASE DEFICIENCY

Miller, W. L., & Morel, Y. (1989) · Annual Review of Genetics

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 127

GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1

Flück, C. E., & Miller, W. L. (2004) · Molecular Endocrinology

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 127

T→A transversion 11 bp from a splice acceptor site in the human gene for steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia

Tee, M.-K., Lin, D., Sugawara, T., Holt, J. A., Guiguen, Y., Buckingham, B., Strauss, J. F., & Miller, W. L. (1995) · Human Molecular Genetics

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 122

Extraadrenal steroid 21-hydroxylation is not mediated by P450c21.

Mellon, S. H., & Miller, W. L. (1989) · Journal of Clinical Investigation

Adrenal Hormones and DisordersHormonal Regulation and Hypertension

Cited by 121

Normal genes for the cholesterol side chain cleavage enzyme, P450scc, in congenital lipoid adrenal hyperplasia

Lin, D., Gitelman, S. E., Saenger, P., & Miller, W. L. (1991) · Journal of Clinical Investigation

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 120

Human P450scc gene transcription is induced by cyclic AMP and repressed by 12-O-tetradecanoylphorbol-13-acetate and A23187 through independent cis elements.

Moore, C. C., Brentano, S. T., & Miller, W. L. (1990) · Molecular and Cellular Biology

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 118

Pharmacogenetics of P450 oxidoreductase: Effect of sequence variants on activities of CYP1A2 and CYP2C19

Agrawal, V., Huang, N., & Miller, W. L. (2008) · Pharmacogenetics and Genomics

Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms

Cited by 117

Genetic and clinical features of P450 oxidoreductase deficiency

Scott, R. R., & Miller, W. L. (2008) · Hormone Research in Paediatrics

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 115

Expression and characterization of truncated human heme oxygenase (hHO-1) and a fusion protein of hHO-1 with human cytochrome P450 reductase

Wilks, A., Black, S. M., Miller, W. L., & Ortiz de Montellano, P. R. (1995) · Biochemistry

Heme Oxygenase-1 and Carbon MonoxideMetal-Catalyzed Oxygenation Mechanisms

Cited by 115

Partial Defect in the Cholesterol Side-Chain Cleavage Enzyme P450scc (CYP11A1) Resembling Nonclassic Congenital Lipoid Adrenal Hyperplasia

Sahakitrungruang, T., Tee, M. K., Blackett, P. R., & Miller, W. L. (2011) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 111

Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus

Gitelman, S. E., Bristow, J., & Miller, W. L. (1992) · Molecular and Cellular Biology

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 106

P450XXI (steroid 21-hydroxylase) gene deletions are not found in family studies of congenital adrenal hyperplasia

Matteson, K. J., Phillips, J. A., Miller, W. L., Chung, B. C., Orlando, P. J., Frisch, H., Ferrandez, A., & Burr, I. M. (1987) · Proceedings of the National Academy of Sciences

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 104