Klein, Allon M.

Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells

Klein, A. M., Mazutis, L., Akartuna, I., Tallapragada, N., Veres, A., Li, V., Peshkin, L., Weitz, D. A., & Kirschner, M. W. (2015) · Cell

Single-cell and spatial transcriptomicsInnovative Microfluidic and Catalytic Techniques Innovation

Cited by 3,356

Scrublet: computational identification of cell doublets in single-cell transcriptomic data

Wolock, S. L., Lopez, R., & Klein, A. M. (2018) · Cell Systems

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 2,758

Scrublet: computational identification of cell doublets in single-cell transcriptomic data

Wolock, S. L., Lopez, R., & Klein, A. M. (2019) · Cell Systems

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 2,758

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

Snippert, H. J., van der Flier, L. G., Sato, T., van Es, J. H., van den Born, M., Kroon-Veenboer, C., Barker, N., Klein, A. M., van Rheenen, J., Simons, B. D., et al. (2010) · Cell

Developmental Biology and Gene RegulationCancer Cells and Metastasis

Cited by 1,951

A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure

Baron, M., Veres, A., Wolock, S. L., Faust, A. L., Gaujoux, R., Vetere, A., Ryu, J. H., Wagner, B. K., Shen-Orr, S. S., Klein, A. M., et al. (2016) · Cell Systems

Single-cell and spatial transcriptomicsPancreatic function and diabetes

Cited by 1,508

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

Plasschaert, L. W., Žilionis, R., Choo-Wing, R., Savova, V., Knehr, J., Roma, G., Klein, A. M., & Jaffe, A. B. (2018) · Nature

Cystic Fibrosis Research AdvancesSingle-cell and spatial transcriptomics

Cited by 1,047

A single type of progenitor cell maintains normal epidermis

Clayton, E., Doupé, D. P., Klein, A. M., Winton, D. J., Simons, B. D., & Jones, P. H. (2007) · Nature

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 853

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

Wagner, D. E., Weinreb, C., Collins, Z. M., Briggs, J. A., Megason, S. G., & Klein, A. M. (2018) · Science

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 849

Lineage tracing on transcriptional landscapes links state to fate during differentiation

Weinreb, C., Rodriguez-Fraticelli, A., Camargo, F. D., & Klein, A. M. (2020) · Science

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 759

Clonal analysis of lineage fate in native haematopoiesis

Rodriguez-Fraticelli, A. E., Wolock, S. L., Weinreb, C. S., Panero, R., Patel, S. H., Jankovic, M., Sun, J., Calogero, R. A., Klein, A. M., & Camargo, F. D. (2018) · Nature

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 596

Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex

Hrvatin, S., Hochbaum, D. R., Nagy, M. A., Cicconet, M., Robertson, K., Cheadle, L., Zilionis, R., Ratner, A., Borges-Monroy, R., Klein, A. M., et al. (2018) · Nature Neuroscience

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 497

Population snapshots predict early haematopoietic and erythroid hierarchies

Tusi, B. K., Wolock, S. L., Weinreb, C., Hwang, Y., Hidalgo, D., Zilionis, R., Waisman, A., Huh, J. R., Klein, A. M., & Socolovsky, M. (2018) · Nature

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 384

Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR

Zemmour, D., Zilionis, R., Kiner, E., Klein, A. M., Mathis, D., & Benoist, C. (2018) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 384

A comprehensive single cell transcriptional landscape of human hematopoietic progenitors

Pellin, D., Loperfido, M., Baricordi, C., Wolock, S. L., Montepeloso, A., Weinberg, O. K., Biffi, A., Klein, A. M., & Biasco, L. (2019) · Nature Communications

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 360

Fundamental limits on dynamic inference from single-cell snapshots

Weinreb, C., Wolock, S., Tusi, B. K., Socolovsky, M., & Klein, A. M. (2018) · Proceedings of the National Academy of Sciences

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 341

SPRING: a kinetic interface for visualizing high dimensional single-cell expression data

Weinreb, C., Wolock, S., & Klein, A. M. (2018) · Bioinformatics

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 298

A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells

Li, L., Bowling, S., McGeary, S. E., Yu, Q., Lemke, B., Alcedo, K., Jia, Y., Liu, X., Ferreira, M., Klein, A. M., et al. (2023) · Cell

Single-cell and spatial transcriptomicsCRISPR and Genetic Engineering

Cited by 167

Mouse embryonic stem cells can differentiate via multiple paths to the same state

Briggs, J. A., Li, V. C., Lee, S., Woolf, C. J., Klein, A., & Kirschner, M. W. (2017) · eLife

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 82

The secreted neuronal signal Spock1 promotes blood-brain barrier development

O’Brown, N. M., Patel, N. B., Hartmann, U., Klein, A. M., Gu, C., & Megason, S. G. (2023) · Developmental Cell

Barrier Structure and Function StudiesZebrafish Biomedical Research Applications

Cited by 33

Fundamental limits on dynamic inference from single cell snapshots

Weinreb, C., Wolock, S., Tusi, B. K., Socolovsky, M., & Klein, A. M. (2017) · bioRxiv (Cold Spring Harbor Laboratory)

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 27

Publisher Correction: Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR

Zemmour, D., Zilionis, R., Kiner, E., Klein, A. M., Mathis, D., & Benoist, C. (2018) · Nature Immunology

T-cell and B-cell ImmunologySingle-cell and spatial transcriptomics

Cited by 5