Hu, Gang

Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits

Xu, Z., Xiao, N., Chen, Y., Huang, H., Marshall, C., Gao, J., Cai, Z., Wu, T., Hu, G., & Xiao, M. (2015) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsCerebrospinal fluid and hydrocephalus

Cited by 500

MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease

Zhou, Y., Lu, M., Du, R.-H., Qiao, C., Jiang, C.-Y., Zhang, K.-Z., Ding, J.-H., & Hu, G. (2016) · Molecular Neurodegeneration

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 455

Small Molecule-Driven NLRP3 Inflammation Inhibition via Interplay between Ubiquitination and Autophagy: Implications for Parkinson Disease

Han, X., Sun, S., Sun, Y., Song, Q., Zhu, J., Song, N., Chen, M., Sun, T., Xia, M., Ding, J., et al. (2019) · Autophagy

Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 408

Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein

Zou, W., Pu, T., Feng, W., Lu, M., Zheng, Y., Du, R., Xiao, M., & Hu, G. (2019) · Translational Neurodegeneration

Parkinson's Disease Mechanisms and TreatmentsCerebrospinal fluid and hydrocephalus

Cited by 396

Extracellular Vesicle–Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models

Yang, L., Han, B., Zhang, Z., Wang, S., Bai, Y., Zhang, Y., Tang, Y., Du, L., Xu, L., Wu, F., et al. (2020) · Circulation

Circular RNAs in diseasesExtracellular vesicles in disease

Cited by 376

Neuroprotective effects of hydrogen sulfide on Parkinson’s disease rat models

Hu, L., Lu, M., Tiong, C. X., Dawe, G. S., Hu, G., & Bian, J. (2010) · Aging Cell

Parkinson's Disease Mechanisms and TreatmentsSulfur Compounds in Biology

Cited by 365

Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142 -TIPARP: implications for cerebral ischemic stroke

Han, B., Zhang, Y., Zhang, Y., Bai, Y., Chen, X., Huang, R., Wu, F., Leng, S., Chao, J., Zhang, J. H., et al. (2018) · Autophagy

Circular RNAs in diseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 360

Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124–2HG

Huang, R., Zhang, Y., Han, B., Bai, Y., Zhou, R., Gan, G., Chao, J., Hu, G., & Yao, H. (2017) · Autophagy

Circular RNAs in diseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 278

Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice

Li, S., Fang, Y., Zhang, Y., Song, M., Zhang, X., Ding, X., Yao, H., Chen, M., Sun, Y., Ding, J., et al. (2022) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 225

The effect of fluoxetine on astrocyte autophagy flux and injured mitochondria clearance in a mouse model of depression

Shu, X., Sun, Y., Sun, X., Zhou, Y., Bian, Y., Shu, Z., Ding, J., Lu, M., & Hu, G. (2019) · Cell Death & Disease

Autophagy in Disease and TherapyTreatment of Major Depression

Cited by 203

CircDYM ameliorates depressive-like behavior by targeting miR-9 to regulate microglial activation via HSP90 ubiquitination

Zhang, Y., Du, L., Bai, Y., Han, B., He, C., Gong, L., Huang, R., Shen, L., Chao, J., Liu, P., et al. (2020) · Molecular Psychiatry

Circular RNAs in diseasesTreatment of Major Depression

Cited by 184

MiR-9 promotes microglial activation by targeting MCPIP1

Yao, H., Ma, R., Yang, L., Hu, G., Chen, X., Duan, M., Kook, Y., Niu, F., Liao, K., Fu, M., et al. (2014) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsMicroRNA in disease regulation

Cited by 158

Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage

Wei, Y., Miao, Q., Zhang, Q., Mao, S., Li, M., Xu, X., Xia, X., Wei, K., Fan, Y., Zheng, X., et al. (2023) · Nature Neuroscience

Cancer, Hypoxia, and MetabolismNeuroscience and Neuropharmacology Research

Cited by 153

The cGAS-STING-YY1 axis accelerates progression of neurodegeneration in a mouse model of Parkinson’s disease via LCN2-dependent astrocyte senescence

Jiang, S.-Y., Tian, T., Yao, H., Xia, X.-M., Wang, C., Cao, L., Hu, G., Du, R.-H., & Lu, M. (2023) · Cell Death & Differentiation

Parkinson's Disease Mechanisms and Treatmentsinterferon and immune responses

Cited by 123

Requirement of AQP4 for antidepressive efficiency of fluoxetine: implication in adult hippocampal neurogenesis

Kong, H., Sha, L.-L., Fan, Y., Xiao, M., Ding, J.-H., Wu, J., & Hu, G. (2009) · Neuropsychopharmacology

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 115

Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT2BR/β-arrestin2 pathway

Fang, Y., Ding, X., Zhang, Y., Cai, L., Ge, Y., Ma, K., Xu, R., Li, S., Song, M., Zhu, H., et al. (2022) · Journal of Neuroinflammation

Tryptophan and brain disordersTreatment of Major Depression

Cited by 96

Plin4-Dependent Lipid Droplets Hamper Neuronal Mitophagy in the MPTP/p-Induced Mouse Model of Parkinson’s Disease

Han, X., Zhu, J., Zhang, X., Song, Q., Ding, J., Lu, M., Sun, S., & Hu, G. (2018) · Frontiers in Neuroscience

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 91

MicroRNA-7 Enhances Subventricular Zone Neurogenesis by Inhibiting NLRP3/Caspase-1 Axis in Adult Neural Stem Cells

Fan, Z., Lu, M., Qiao, C., Zhou, Y., Ding, J.-H., & Hu, G. (2016) · Molecular Neurobiology

Neurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 76

Aquaporin‐4 Knockout Exacerbates Corticosterone‐Induced Depression by Inhibiting Astrocyte Function and Hippocampal Neurogenesis

Kong, H., Zeng, X., Fan, Y., Yuan, S., Ge, S., Xie, W., Wang, H., & Hu, G. (2014) · CNS Neuroscience & Therapeutics

Ion Transport and Channel RegulationStress Responses and Cortisol

Cited by 72

Neuronal SH2B1 attenuates apoptosis in an MPTP mouse model of Parkinson's disease via promoting PLIN4 degradation

Han, X., Liu, Y., Dai, Y., Xu, T., Hu, Q., Yi, X., Rui, L., Hu, G., & Hu, J. (2022) · Redox Biology

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 42

Cspg4 high microglia contribute to microgliosis during neurodegeneration

Liu, Y.-J., Ding, Y., Yin, Y.-Q., Xiao, H., Hu, G., & Zhou, J.-W. (2023) · Proceedings of the National Academy of Sciences

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 14