MiR-9 promotes microglial activation by targeting MCPIP1
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Anti-miR-9 microinjection inactivates microglia in the CNS upon LPS stimulation, resulting in alleviated neuroinflammation in mice.
“In addition, anti-miR-9 microinjection inactivated microglia in the CNS upon LPS stimulation, resulting in alleviated neuroinflammation in mice [52].”
From Neuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression (2022) · cites this paper as [52]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827 · see citing works
ATP mediates rapid microglial response to local brain injury in vivo
Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913 · see citing works
Ponomarev, E. D., Veremeyko, T., Barteneva, N., Krichevsky, A. M., & Weiner, H. L. (2011) · Nature Medicine · doi:10.1038/nm.2266 · Cited by 787 · see citing works
Bazzoni, F., Rossato, M., Fabbri, M., Gaudiosi, D., Mirolo, M., Mori, L., Tamassia, N., Mantovani, A., Cassatella, M. A., & Locati, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810909106 · Cited by 548 · see citing works
Cardoso, A. L., Guedes, J. R., Pereira de Almeida, L., & Pedroso de Lima, M. C. (2012) · Immunology · doi:10.1111/j.1365-2567.2011.03514.x · Cited by 336 · see citing works
Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge
Wynne, A. M., Henry, C. J., Huang, Y., Cleland, A., & Godbout, J. P. (2010) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.05.011 · Cited by 224 · see citing works
Fenn, A. M., Henry, C. J., Huang, Y., Dugan, A., & Godbout, J. P. (2012) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2011.10.003 · Cited by 198 · see citing works
Flagged first, then by citations
Research works printed but not linked: 39
- Rostasy K. M. Inflammation and neuroaxonal injury in multiple sclerosis and AIDS dementia complex: implications for neuroprotective treatment. Neuropediatrics 36, 230– 239 (2005). 16138246
- Prineas J. W. & Parratt J. D. Oligodendrocytes and the early multiple sclerosis lesion. Ann. Neurol. 72, 18– 31 (2012). 22829266
- Ransohoff R. M. & Cardona A. E. The myeloid cells of the central nervous system parenchyma. Nature 468, 253– 262 (2010). 21068834
- Doorn K. J.. Emerging roles of microglial activation and non-motor symptoms in Parkinson’s disease. Prog. Neurobiol. 98, 222– 238 (2012). 22732265
- Varnum M. M. & Ikezu T. The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer’s disease brain. Arch. Immunol. Ther. Exp. (Warsz) 60, 251– 266 (2012). 22710659 PMC4429536
- D’Aversa T. G., Eugenin E. A. & Berman J. W. NeuroAIDS: contributions of the human immunodeficiency virus-1 proteins Tat and gp120 as well as CD40 to microglial activation. J. Neurosci. Res. 81, 436– 446 (2005). 15954144
- Yenari M. A., Kauppinen T. M. & Swanson R. A. Microglial activation in stroke: therapeutic targets. Neurotherapeutics 7, 378– 391 (2010). 20880502 PMC5084300
- O’Connell R. M., Rao D. S. & Baltimore D. MicroRNA regulation of inflammatory responses. Annu. Rev. Immunol. 30, 295– 312 (2012). 22224773
- Bartel D. P. & Chen C. Z. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5, 396– 400 (2004). 15143321
- Calin G. A. & Croce C. M. MicroRNA signatures in human cancers. Nat. Rev. Cancer 6, 857– 866 (2006). 17060945
- O'Neill L. A., Sheedy F. J. & McCoy C. E. MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat. Rev. Immunol. 11, 163– 175 (2011). 21331081
- Johnnidis J. B.. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 451, 1125– 1129 (2008). 18278031
- O’Connell R. M.. Physiological and pathological roles for microRNAs in the immune system. Nat. Rev. Immunol. 10, 111– 122 (2010). 20098459
- Ponomarev E. D., Veremeyko T. & Weiner H. L. MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS. Glia 61, 91– 103 (2013). 22653784 PMC3434289
- Delaloy C.. MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell 6, 323– 335 (2010). 20362537 PMC2851637
- Zhao C.. A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat. Struct. Mol. Biol. 16, 365– 371 (2009). 19330006 PMC2667220
- Tan S. L.. MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain. Genes Cells 17, 952– 961 (2012). 23134481
- Dajas-Bailador F.. microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons. Nat. Neurosci. 15, 697– 699 (2012). 22484572
- Zhou L.. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ. Res. 98, 1177– 1185 (2006). 16574901 PMC1523425
- Liang J.. A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages. J. Biol. Chem. 283, 6337– 6346 (2008). 18178554
- Stevens S. L.. Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury. J. Neurosci. 31, 8456– 8463 (2011). 21653850 PMC3130521
- Matsushita K.. Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. Nature 458, 1185– 1190 (2009). 19322177
- Liang J.. Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation. PLoS ONE 3, e2880 (2008). 18682727 PMC2478707
- Liang J.. MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling. J. Exp. Med. 207, 2959– 2973 (2010). 21115689 PMC3005225
- Liang J.. Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines. J. Neuroinflammation 8, 182 (2011). 22196138 PMC3260209
- Ma L.. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat. Cell Biol. 12, 247– 256 (2010). 20173740 PMC2845545
- Winter J.. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat. Cell Biol. 11, 228– 234 (2009). 19255566
- Fang Z. & Rajewsky N. The impact of miRNA target sites in coding sequences and in 3′UTRs. PLoS ONE 6, e18067 (2011). 21445367 PMC3062573
- Hausser J.. Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation. Genome Res. 23, 604– 615 (2013). 23335364 PMC3613578
- Wienholds E.. MicroRNA expression in zebrafish embryonic development. Science 309, 310– 311 (2005). 15919954
- Leucht C.. MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nat. Neurosci. 11, 641– 648 (2008). 18454145
- Shibata M.. MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J. Neurosci. 31, 3407– 3422 (2011). 21368052 PMC6623912
- Bonev B., Stanley P. & Papalopulu N. MicroRNA-9 modulates Hes1 ultradian oscillations by forming a double-negative feedback loop. Cell Rep. 2, 10– 18 (2012). 22840391 PMC4103481
- Wan H. Y.. Regulation of the transcription factor NF-kappaB1 by microRNA-9 in human gastric adenocarcinoma. Mol. Cancer 9, 16 (2010). 20102618 PMC2835654
- Akerblom M.. Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9. Nat. Commun. 4, 1770 (2013). 23612311
- Jung S.. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell Biol. 20, 4106– 4114 (2000). 10805752 PMC85780
- Yao H.. Involvement of TRPC channels in CCL2-mediated neuroprotection against tat toxicity. J. Neurosci. 29, 1657– 1669 (2009). 19211873 PMC2768421
- Hu G.. MicroRNA-98 and let-7 regulate expression of suppressor of cytokine signaling 4 in biliary epithelial cells in response to Cryptosporidium parvum infection. J. Infect. Dis. 202, 125– 135 (2010). 20486857 PMC2880649
- Wohleb E. S.. beta-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat. J. Neurosci. 31, 6277– 6288 (2011). 21525267 PMC3160240
Cited by
Sorted by citations
Han, B., Zhang, Y., Zhang, Y., Bai, Y., Chen, X., Huang, R., Wu, F., Leng, S., Chao, J., Zhang, J. H., et al. (2018) · Autophagy · doi:10.1080/15548627.2018.1458173 · Cited by 360 · see citing works
Self-citationAging, melatonin, and the pro- and anti-inflammatory networks
Hardeland, R. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051223 · Cited by 337 · see citing works
Role of circular RNAs in brain development and CNS diseases
Mehta, S. L., Dempsey, R. J., & Vemuganti, R. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101746 · Cited by 281 · see citing works
Huang, R., Zhang, Y., Han, B., Bai, Y., Zhou, R., Gan, G., Chao, J., Hu, G., & Yao, H. (2017) · Autophagy · doi:10.1080/15548627.2017.1356975 · Cited by 278 · see citing works
Self-citationZhang, Y., Du, L., Bai, Y., Han, B., He, C., Gong, L., Huang, R., Shen, L., Chao, J., Liu, P., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-018-0285-0 · Cited by 184 · see citing works
Self-citationNeuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression
Xian, X., Cai, L.-L., Li, Y., Wang, R.-C., Xu, Y.-H., Chen, Y.-J., Xie, Y.-H., Zhu, X.-L., & Li, Y.-F. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01332-w · Cited by 169 · see citing works
Chen, X., Jiang, M., Li, H., Wang, Y., Shen, H., Li, X., Zhang, Y., Wu, J., Yu, Z., & Chen, G. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01882-6 · Cited by 85 · see citing works
Self-citation
- Authors
- Yao, H., Ma, R., Yang, L., Hu, G., Chen, X., Duan, M., Kook, Y., Niu, F., Liao, K., Fu, M., Hu, G., Kolattukudy, P., & Buch, S.
- Venue
- Nature Communications
- Published
- 2014-07-14
- Volume
- 5
- Issue
- 1
- ISSN
- 2041-1723
- PMC
- PMC4104446
- Cited by
- 146
- References
- 7
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review