Patsopoulos, Nikolaos A.

Genetic and epigenetic fine mapping of causal autoimmune disease variants

Farh, K. K.-H., Marson, A., Zhu, J., Kleinewietfeld, M., Housley, W. J., Beik, S., Shoresh, N., Whitton, H., Ryan, R. J. H., Shishkin, A. A., et al. (2015) · Nature

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 1,956

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., et al. (2018) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,924

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

International Multiple Sclerosis Genetics Consortium, Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., et al. (2019) · Science

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 1,471

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., et al. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,303

Uncertainty in heterogeneity estimates in meta-analyses

Ioannidis, J. P. A., Patsopoulos, N. A., & Evangelou, E. (2007) · BMJ

Meta-analysis and systematic reviewsStatistical Methods in Epidemiology

Cited by 1,254

A pragmatic view on pragmatic trials

Patsopoulos, N. A. (2011) · Dialogues in Clinical Neuroscience

Statistical Methods in Clinical TrialsHealth Policy Implementation Science

Cited by 844

Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

Raj, T., Rothamel, K., Mostafavi, S., Ye, C., Lee, M. N., Replogle, J. M., Feng, T., Lee, M., Asinovski, N., Frohlich, I., et al. (2014) · Science

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 506

Reasons or excuses for avoiding meta-analysis in forest plots

Ioannidis, J. P. A., Patsopoulos, N. A., & Rothstein, H. R. (2008) · BMJ

Meta-analysis and systematic reviewsStatistical Methods in Epidemiology

Cited by 457

Genome‐wide meta‐analysis identifies novel multiple sclerosis susceptibility loci

Patsopoulos, N. A., the Bayer Pharma MS Genetics Working Group, T. S. C. O. S. E. I. A. A. C., & de Bakker, P. I. W. (2011) · Annals of Neurology

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 353

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

Tam, O. H., Rozhkov, N. V., Shaw, R., Kim, D., Hubbard, I., Fennessey, S., Propp, N., Phatnani, H., Kwan, J., Sareen, D., et al. (2019) · Cell Reports

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 327

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

Patsopoulos, N. A., Barcellos, L. F., Hintzen, R. Q., Schaefer, C., van Duijn, C. M., Noble, J. A., Raj, T., IMSGC, ANZgene, Gourraud, P.-A., et al. (2013) · PLoS Genetics

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 312

Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types

Chun, S., Casparino, A., Patsopoulos, N. A., Croteau-Chonka, D. C., Raby, B. A., De Jager, P. L., Sunyaev, S. R., & Cotsapas, C. (2017) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 259

Locus for severity implicates CNS resilience in progression of multiple sclerosis

International Multiple Sclerosis Genetics Consortium, Harroud, A., Stridh, P., McCauley, J. L., Saarela, J., van den Bosch, A. M. R., Engelenburg, H. J., Beecham, A. H., Alfredsson, L., Alikhani, K., et al. (2023) · Nature

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 243

Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region

Wissemann, W. T., Hill-Burns, E. M., Zabetian, C. P., Factor, S. A., Patsopoulos, N., Hoglund, B., Holcomb, C., Donahue, R. J., Thomson, G., Erlich, H., et al. (2013) · The American Journal of Human Genetics

Parkinson's Disease Mechanisms and TreatmentsGenetic Associations and Epidemiology

Cited by 189

Claims of Sex Differences: An Empirical Assessment in Genetic Associations

Patsopoulos, N. A., Tatsioni, A., & Ioannidis, J. P. A. (2007) · JAMA

Sex and Gender in HealthcareGenetic Associations and Epidemiology

Cited by 150

Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies

Siontis, K. C. M., Patsopoulos, N. A., & Ioannidis, J. P. A. (2010) · European Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 117

Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury

Izzy, S., Liu, Q., Fang, Z., Lule, S., Wu, L., Chung, J. Y., Sarro-Schwartz, A., Brown-Whalen, A., Perner, C., Hickman, S. E., et al. (2019) · Frontiers in Cellular Neuroscience

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 110

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies

George, M. F., Briggs, F. B. S., Shao, X., Gianfrancesco, M. A., Kockum, I., Harbo, H. F., Celius, E. G., Bos, S. D., Hedström, A., Shen, L., et al. (2016) · Neurology Genetics

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 86

The chromatin landscape of Th17 cells reveals mechanisms of diversification of regulatory and pro-inflammatory states

Thakore, P. I., Schnell, A., Zhao, M., Huang, L., Hou, Y., Christian, E., Zaghouani, S., Wang, C., Singh, V., Ma, S., et al. (2022) · Nature Immunology

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 57

Heterogeneous views on heterogeneity

Patsopoulos, N. A., Evangelou, E., & Ioannidis, J. P. (2009) · International Journal of Epidemiology

Meta-analysis and systematic reviewsStatistical Methods in Epidemiology

Cited by 35

Sex differences in progressive multiple sclerosis brain gene expression in oligodendrocytes and OPCs

LaBarre, B. A., King, D., Ploumakis, A., Pinzon, A. M., Guttmann, C. R. G., Patsopoulos, N., & Chitnis, T. (2025) · BMC Medical Genomics

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 4