Hartl, Dominik

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

Kormann, M. S. D., Hasenpusch, G., Aneja, M. K., Nica, G., Flemmer, A. W., Herber-Jonat, S., Huppmann, M., Mays, L. E., Illenyi, M., Schams, A., et al. (2011) · Nature Biotechnology

RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms

Cited by 733

Competition between DNA methylation and transcription factors determines binding of NRF1

Domcke, S., Bardet, A. F., Adrian Ginno, P., Hartl, D., Burger, L., & Schübeler, D. (2015) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 508

Immune mechanisms in pulmonary fibrosis

Kolahian, S., Fernandez, I. E., Eickelberg, O., & Hartl, D. (2016) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTransplantation: Methods and Outcomes

Cited by 349

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

Jüttner, J., Szabo, A., Gross-Scherf, B., Morikawa, R. K., Rompani, S. B., Hantz, P., Szikra, T., Esposti, F., Cowan, C. S., Bharioke, A., et al. (2019) · Nature Neuroscience

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 218

Extrapulmonary Aspergillus infection in patients with CARD9 deficiency

Rieber, N., Gazendam, R. P., Freeman, A. F., Hsu, A. P., Collar, A. L., Sugui, J. A., Drummond, R. A., Rongkavilit, C., Hoffman, K., Henderson, C., et al. (2016) · JCI Insight

Immunodeficiency and Autoimmune DisordersAntifungal resistance and susceptibility

Cited by 171

Localization and Functionality of the Inflammasome in Neutrophils

Bakele, M., Joos, M., Burdi, S., Allgaier, N., Pöschel, S., Fehrenbacher, B., Schaller, M., Marcos, V., Kümmerle-Deschner, J., Rieber, N., et al. (2014) · Journal of Biological Chemistry

Inflammasome and immune disordersNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 157

In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency

Mahiny, A. J., Dewerth, A., Mays, L. E., Alkhaled, M., Mothes, B., Malaeksefat, E., Loretz, B., Rottenberger, J., Brosch, D. M., Reautschnig, P., et al. (2015) · Nature Biotechnology

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 139

Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism

Mays, L. E., Ammon-Treiber, S., Mothes, B., Alkhaled, M., Rottenberger, J., Müller-Hermelink, E. S., Grimm, M., Mezger, M., Beer-Hammer, S., von Stebut, E., et al. (2013) · Journal of Clinical Investigation

Asthma and respiratory diseasesAllergic Rhinitis and Sensitization

Cited by 113

Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis

Fernandez, I. E., Greiffo, F. R., Frankenberger, M., Bandres, J., Heinzelmann, K., Neurohr, C., Hatz, R., Hartl, D., Behr, J., & Eickelberg, O. (2016) · European Respiratory Journal

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisImmune cells in cancer

Cited by 75

Cis-regulatory landscapes of four cell types of the retina

Hartl, D., Krebs, A. R., Jüttner, J., Roska, B., & Schübeler, D. (2017) · Nucleic Acids Research

Genomics and Chromatin DynamicsRetinal Development and Disorders

Cited by 37