Jacobs, Heinz

Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity.

Vujanovic, M., Krietsch, J., Raso, M. C., Terraneo, N., Zellweger, R., Schmid, J. A., Taglialatela, A., Huang, J.-W., Holland, C. L., Zwicky, K., et al. (2017) · Molecular Cell

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 227

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

Hendel, A., Krijger, P. H. L., Diamant, N., Goren, Z., Langerak, P., Kim, J., Reißner, T., Lee, K.-Y., Geacintov, N. E., Carell, T., et al. (2011) · PLoS Genetics

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 132

Temporally distinct translesion synthesis pathways for ultraviolet light-induced photoproducts in the mammalian genome

Temviriyanukul, P., van Hees-Stuivenberg, S., Delbos, F., Jacobs, H., de Wind, N., & Jansen, J. G. (2012) · DNA Repair

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 41

AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress

Villafañez, F., García, I. A., Carbajosa, S., Pansa, M. F., Mansilla, S., Llorens, M. C., Angiolini, V., Guantay, L., Jacobs, H., Madauss, K. P., et al. (2019) · Oncogene

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 30