Newman, Anthony

Allosteric activation of CRISPR-Cas12a requires the concerted movement of the bridge helix and helix 1 of the RuvC II domain

Wörle, E., Newman, A., Burgio, G., & Grohmann, D. (2022) · Nucleic Acids Research

CRISPR and Genetic EngineeringDNA and Nucleic Acid Chemistry

Cited by 32

Allosteric activation of CRISPR-Cas12a requires the concerted movement of the bridge helix and helix 1 of the RuvC II domain

Wörle, E., Newman, A., D’Silva, J., Burgio, G., & Grohmann, D. (2022) · Nucleic Acids Research

CRISPR and Genetic EngineeringDNA and Nucleic Acid Chemistry

Cited by 32

CRISPR-Cas12a REC2–Nuc interactions drive target-strand cleavage and constrain trans cleavage

Newman, A., Saha, A., Starrs, L., Arantes, P. R., Palermo, G., & Burgio, G. (2025) · Nucleic Acids Research

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 14

CRISPR-Cas12a REC2 – NUC interactions drive target-strand cleavage and constrain trans cleavage

Newman, A., Saha, A., Starrs, L., Arantes, P. R., Palermo, G., & Burgio, G. (2025) · Nucleic Acids Research

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 14