Lemke, Greg

Microglia states and nomenclature: A field at its crossroads

Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., et al. (2022) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,973

TAM Receptors Are Pleiotropic Inhibitors of the Innate Immune Response

Rothlin, C. V., Ghosh, S., Zuniga, E. I., Oldstone, M. B. A., & Lemke, G. (2007) · Cell

Immune Response and InflammationPhagocytosis and Immune Regulation

Cited by 1,055

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

Nicolás-Ávila, J. A., Lechuga-Vieco, A. V., Esteban-Martínez, L., Sánchez-Díaz, M., Díaz-García, E., Santiago, D. J., Rubio-Ponce, A., Li, J. L., Balachander, A., Quintana, J. A., et al. (2020) · Cell

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

Cited by 762

TAM receptors regulate multiple features of microglial physiology

Fourgeaud, L., Través, P. G., Tufail, Y., Leal-Bailey, H., Lew, E. D., Burrola, P. G., Callaway, P., Zagórska, A., Rothlin, C. V., Nimmerjahn, A., et al. (2016) · Nature

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 600

Biology of the TAM Receptors

Lemke, G. (2013) · Cold Spring Harbor Perspectives in Biology

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 598

Tyro-3 family receptors are essential regulators of mammalian spermatogenesis

Lu, Q., Gore, M., Zhang, Q., Camenisch, T., Boast, S., Casagranda, F., Lai, C., Skinner, M. K., Klein, R., Matsushima, G. K., et al. (1999) · Nature

Sperm and Testicular FunctionReproductive Biology and Fertility

Cited by 514

Microglia use TAM receptors to detect and engulf amyloid β plaques

Huang, Y., Happonen, K. E., Burrola, P. G., O’Connor, C., Hah, N., Huang, L., Nimmerjahn, A., & Lemke, G. (2021) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 483

An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system

Lai, C., & Lemke, G. (1991) · Neuron

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 443

Microglia Actively remodel adult hippocampal neurogenesis through the phagocytosis secretome

Diaz-Aparicio, I., Paris, I., Sierra-Torre, V., Plaza-Zabala, A., Rodríguez-Iglesias, N., Márquez-Ropero, M., Beccari, S., Huguet, P., Abiega, O., Alberdi, E., et al. (2020) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 333

TAM receptor function in the retinal pigment epithelium

Prasad, D., Rothlin, C. V., Burrola, P., Burstyn-Cohen, T., Lu, Q., Garcia de Frutos, P., & Lemke, G. (2006) · Molecular and Cellular Neuroscience

Retinal Development and DisordersPhagocytosis and Immune Regulation

Cited by 270

Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis

Burstyn-Cohen, T., Lew, E. D., Través, P. G., Burrola, P. G., Hash, J. C., & Lemke, G. (2012) · Neuron

Phagocytosis and Immune RegulationRetinal Development and Disorders

Cited by 163

The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

Miner, J. J., Daniels, B. P., Shrestha, B., Proenca-Modena, J. L., Lew, E. D., Lazear, H. M., Gorman, M. J., Lemke, G., Klein, R. S., & Diamond, M. S. (2015) · Nature Medicine

Phagocytosis and Immune RegulationBarrier Structure and Function Studies

Cited by 152

Retinal input instructs alignment of visual topographic maps

Triplett, J. W., Owens, M. T., Yamada, J., Lemke, G., Cang, J., Stryker, M. P., & Feldheim, D. A. (2009) · Cell

Axon Guidance and Neuronal SignalingVisual perception and processing mechanisms

Cited by 123

Retinotectal mapping: new insights from molecular genetics

Lemke, G., & Reber, M. (2005) · Annual Review of Cell and Developmental Biology

Axon Guidance and Neuronal SignalingDevelopmental Biology and Gene Regulation

Cited by 108

The dense-core plaques of Alzheimer’s disease are granulomas

Lemke, G., & Huang, Y. (2022) · Journal of Experimental Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 37

Microglial phagocytosis in Alzheimer disease

Brown, G. C., St George-Hyslop, P., Paolicelli, R. C., & Lemke, G. (2026) · Nature Reviews Neurology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 36