Okita, Keisuke

A more efficient method to generate integration-free human iPS cells

Okita, K., Matsumura, Y., Sato, Y., Okada, A., Morizane, A., Okamoto, S., Hong, H., Nakagawa, M., Tanabe, K., Tezuka, K.-I., et al. (2011) · Nature Methods

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 2,061

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

Hong, H., Takahashi, K., Ichisaka, T., Aoi, T., Kanagawa, O., Nakagawa, M., Okita, K., & Yamanaka, S. (2009) · Nature

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 1,301

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

Kondo, T., Asai, M., Tsukita, K., Kutoku, Y., Ohsawa, Y., Sunada, Y., Imamura, K., Egawa, N., Yahata, N., Okita, K., et al. (2013) · Cell Stem Cell

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 741

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model

Kikuchi, T., Morizane, A., Doi, D., Magotani, H., Onoe, H., Hayashi, T., Mizuma, H., Takara, S., Takahashi, R., Inoue, H., et al. (2017) · Nature

Pluripotent Stem Cells ResearchParkinson's Disease Mechanisms and Treatments

Cited by 702

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

Xu, H., Wang, B., Ono, M., Kagita, A., Fujii, K., Sasakawa, N., Ueda, T., Gee, P., Nishikawa, M., Nomura, M., et al. (2019) · Cell stem cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 581

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

Ohnishi, K., Semi, K., Yamamoto, T., Shimizu, M., Tanaka, A., Mitsunaga, K., Okita, K., Osafune, K., Arioka, Y., Maeda, T., et al. (2014) · Cell

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 460

MHC matching improves engraftment of iPSC-derived neurons in non-human primates

Morizane, A., Kikuchi, T., Hayashi, T., Mizuma, H., Takara, S., Doi, H., Mawatari, A., Glasser, M. F., Shiina, T., Ishigaki, H., et al. (2017) · Nature Communications

Pluripotent Stem Cells ResearchOrgan and Tissue Transplantation Research

Cited by 244

Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity

Nishizawa, M., Chonabayashi, K., Nomura, M., Tanaka, A., Nakamura, M., Inagaki, A., Nishikawa, M., Takei, I., Oishi, A., Tanabe, K., et al. (2016) · Cell stem cell

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 234

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts

Tsubooka, N., Ichisaka, T., Okita, K., Takahashi, K., Nakagawa, M., & Yamanaka, S. (2009) · Genes to Cells

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 154

Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates

Kawamura, T., Miyagawa, S., Fukushima, S., Maeda, A., Kashiyama, N., Kawamura, A., Miki, K., Okita, K., Yoshida, Y., Shiina, T., et al. (2016) · Stem Cell Reports

Pluripotent Stem Cells ResearchTransplantation: Methods and Outcomes

Cited by 145