Hopkins, Benjamin D.

The PI3K Pathway in Human Disease

Fruman, D. A., Chiu, H., Hopkins, B. D., Bagrodia, S., Cantley, L. C., & Abraham, R. T. (2017) · Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,749

An atlas of substrate specificities for the human serine/threonine kinome

Johnson, J. L., Yaron, T. M., Huntsman, E. M., Kerelsky, A., Song, J., Regev, A., Lin, T.-Y., Liberatore, K., Cizin, D. M., Cohen, B. M., et al. (2023) · Nature

Advanced Proteomics Techniques and ApplicationsProtein Kinase Regulation and GTPase Signaling

Cited by 728

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

Hopkins, B. D., Pauli, C., Du, X., Wang, D. G., Li, X., Wu, D., Amadiume, S. C., Goncalves, M. D., Hodakoski, C., Lundquist, M. R., et al. (2018) · Nature

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 706

Phosphatidylinositol 3-kinase, growth disorders, and cancer

Goncalves, M. D., Hopkins, B. D., & Cantley, L. C. (2018) · New England Journal of Medicine

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 327

PTEN function: the long and the short of it

Hopkins, B. D., Hodakoski, C., Barrows, D., Mense, S. M., & Parsons, R. E. (2014) · Trends in Biochemical Sciences

PI3K/AKT/mTOR signaling in cancerProtein Tyrosine Phosphatases

Cited by 309

Insulin–PI3K signalling: an evolutionarily insulated metabolic driver of cancer

Hopkins, B. D., Goncalves, M. D., & Cantley, L. C. (2020) · Nature Reviews Endocrinology

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 288

Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina

Sun, J., Hopkins, B. D., Tsujikawa, K., Perruzzi, C., Adini, I., Swerlick, R., Bornstein, P., Lawler, J., & Benjamin, L. E. (2009) · American Journal of Physiology-Heart and Circulatory Physiology

Angiogenesis and VEGF in CancerRetinal Diseases and Treatments

Cited by 56