Carragher, Neil O.

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

Ramachandran, P., Dobie, R., Wilson-Kanamori, J. R., Dora, E. F., Henderson, B. E. P., Luu, N. T., Portman, J. R., Matchett, K. P., Brice, M., Marwick, J. A., et al. (2019) · Nature

Liver physiology and pathologyLiver Diseases and Immunity

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Screening out irrelevant cell-based models of disease

Horvath, P., Aulner, N., Bickle, M., Davies, A. M., Nery, E. D., Ebner, D., Montoya, M. C., Östling, P., Pietiäinen, V., Price, L. S., et al. (2016) · Nature Reviews Drug Discovery

Animal testing and alternatives3D Printing in Biomedical Research

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Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530

Green, T. P., Fennell, M., Whittaker, R., Curwen, J., Jacobs, V., Allen, J., Logie, A., Hargreaves, J., Hickinson, D. M., Wilkinson, R. W., et al. (2009) · Molecular Oncology

Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling

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Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

Girotti, M. R., Lopes, F., Preece, N., Niculescu-Duvaz, D., Zambon, A., Davies, L., Whittaker, S., Saturno, G., Viros, A., Pedersen, M., et al. (2015) · Cancer Cell

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

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Multimodal decoding of human liver regeneration

Matchett, K. P., Wilson-Kanamori, J. R., Portman, J. R., Kapourani, C. A., Fercoq, F., May, S., Zajdel, E., Beltran, M., Sutherland, E. F., Mackey, J. B. G., et al. (2024) · Nature

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

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Discovery of senolytics using machine learning

Smer-Barreto, V., Quintanilla, A., Elliott, R. J. R., Dawson, J. C., Sun, J., Campa, V. M., Lorente-Macías, Á., Unciti-Broceta, A., Carragher, N. O., Acosta, J. C., et al. (2023) · Nature Communications

Computational Drug Discovery MethodsTelomeres, Telomerase, and Senescence

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Evolution and impact of high content imaging.

Way, G. P., Sailem, H., Shave, S., Kasprowicz, R., & Carragher, N. O. (2023) · SLAS Discovery

Cell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques

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High-content phenotypic and pathway profiling to advance drug discovery in diseases of unmet need

Hughes, R. E., Elliott, R. J. R., Dawson, J. C., & Carragher, N. O. (2021) · Cell Chemical Biology

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

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