Kufe, Donald

Translocation of SAPK/JNK to Mitochondria and Interaction with Bcl-xL in Response to DNA Damage

Kharbanda, S., Saxena, S., Yoshida, K., Pandey, P., Kaneki, M., Wang, Q., Cheng, K., Chen, Y.-N., Campbell, A., Sudha, T., et al. (2000) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 429

A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas

Hong, D. S., Kurzrock, R., Supko, J. G., He, X., Naing, A., Wheler, J., Lawrence, D., Eder, J. P., Meyer, C. J., Ferguson, D. A., et al. (2012) · Clinical Cancer Research

Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents

Cited by 236

Lenalidomide enhances anti-myeloma cellular immunity

Luptakova, K., Rosenblatt, J., Glotzbecker, B., Mills, H., Stroopinsky, D., Kufe, T., Vasir, B., Arnason, J., Tzachanis, D., Zwicker, J. I., et al. (2013) · Cancer Immunology, Immunotherapy

Multiple Myeloma Research and TreatmentsImmunotherapy and Immune Responses

Cited by 162

The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism

Ito, Y., Pandey, P., Sporn, M. B., Datta, R., Kharbanda, S., & Kufe, D. (2001) · Molecular Pharmacology

Cell death mechanisms and regulationNatural product bioactivities and synthesis

Cited by 138

Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3

Ahmad, R., Raina, D., Meyer, C., & Kufe, D. (2008) · Cancer Research

Cytokine Signaling Pathways and InteractionsNatural product bioactivities and synthesis

Cited by 120

Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells

Ito, Y., Mishra, N. C., Yoshida, K., Kharbanda, S., Saxena, S., & Kufe, D. (2001) · Cell Death & Differentiation

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 62

Inhibition of phorbol ester‐induced monocytic differentiation by dexamethasone is associated with down‐regulation of c‐fos and c‐jun (AP‐1)

Hass, R., Brach, M., Kharbanda, S., Giese, G., Traub, P., & Kufe, D. (1991) · Journal of Cellular Physiology

Retinoids in leukemia and cellular processesEstrogen and related hormone effects

Cited by 31

Anti-MUC1-C Antibody-Conjugated Nanoparticles Potentiate the Efficacy of Fractionated Radiation Therapy

Detappe, A., Mathieu, C., Jin, C., Agius, M. P., Diringer, M.-C., Tran, V.-L., Pivot, X., Lux, F., Tillement, O., Kufe, D., et al. (2020) · International Journal of Radiation Oncology*Biology*Physics

Radiation Therapy and DosimetryRadiopharmaceutical Chemistry and Applications

Cited by 27

Identification of Topoisomerase I Mutations Affecting Both DNA Cleavage and Interaction with Camptothecina

LI, X., HALUSKA, P., HSIANG, Y., BHARTI, A., KUFE, D. W., & RUBIN, E. H. (1996) · Annals of the New York Academy of Sciences

Cancer therapeutics and mechanismsBioactive Compounds and Antitumor Agents

Cited by 21