Poon, Gregory M.K.

PU.1 controls fibroblast polarization and tissue fibrosis

Wohlfahrt, T., Rauber, S., Uebe, S., Luber, M., Soare, A., Ekici, A., Weber, S., Matei, A.-E., Chen, C.-W., Maier, C., et al. (2019) · Nature

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 187

Pharmacological inhibition of the transcription factor PU.1 in leukemia

Antony-Debré, I., Paul, A., Leite, J., Mitchell, K., Kim, H. M., Carvajal, L. A., Todorova, T. I., Huang, K., Kumar, A., Farahat, A. A., et al. (2017) · Journal of Clinical Investigation

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 120

Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients

Le Coz, C., Nguyen, D. N., Su, C., Nolan, B. E., Albrecht, A. V., Xhani, S., Sun, D., Demaree, B., Pillarisetti, P., Khanna, C., et al. (2021) · Journal of Experimental Medicine

Immunodeficiency and Autoimmune DisordersGenomics and Chromatin Dynamics

Cited by 69

Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines

Munde, M., Wang, S., Kumar, A., Stephens, C. E., Farahat, A. A., Boykin, D. W., Wilson, W. D., & Poon, G. M. K. (2014) · Nucleic Acids Research

DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties

Cited by 68

Differential sensitivity to methylated DNA by ETS-family transcription factors is intrinsically encoded in their DNA-binding domains

Stephens, D. C., & Poon, G. M. K. (2016) · Nucleic Acids Research

Epigenetics and DNA MethylationDNA and Nucleic Acid Chemistry

Cited by 37

Base Coupling in Sequence-specific Site Recognition by the ETS Domain of Murine PU.1

Poon, G. M. K., & Macgregor, R. B. (2003) · Journal of Molecular Biology

DNA and Nucleic Acid ChemistryDiffusion and Search Dynamics

Cited by 29

Pharmacological Restriction of Genomic Binding Sites Redirects PU.1 Pioneer Transcription Factor Activity

Taylor, S. J., Stauber, J., Bohorquez, O., Tatsumi, G., Kumari, R., Chakraborty, J., Bartholdy, B. A., Schwenger, E., Sundaravel, S., Farahat, A. A., et al. (2024) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 22

A Thermodynamic Basis of DNA Sequence Selectivity by the ETS Domain of Murine PU.1

Poon, G. M. K., & Macgregor, R. B. (2004) · Journal of Molecular Biology

DNA and Nucleic Acid ChemistryDiffusion and Search Dynamics

Cited by 19