Tsuda, Makoto

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

Coull, J. A. M., Beggs, S., Boudreau, D., Boivin, D., Tsuda, M., Inoue, K., Gravel, C., Salter, M. W., & De Koninck, Y. (2005) · Nature

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,965

Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential

Inoue, K., & Tsuda, M. (2018) · Nature Reviews Neuroscience

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 908

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

Koizumi, S., Shigemoto-Mogami, Y., Nasu-Tada, K., Shinozaki, Y., Ohsawa, K., Tsuda, M., Joshi, B. V., Jacobson, K. A., Kohsaka, S., & Inoue, K. (2007) · Nature

Adenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 802

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

Masuda, T., Tsuda, M., Yoshinaga, R., Tozaki-Saitoh, H., Ozato, K., Tamura, T., & Inoue, K. (2012) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsPain Mechanisms and Treatments

Cited by 338

Specification of CNS macrophage subsets occurs postnatally in defined niches

Masuda, T., Amann, L., Monaco, G., Sankowski, R., Staszewski, O., Krueger, M., Del Gaudio, F., He, L., Paterson, N., Nent, E., et al. (2022) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 294

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

Konishi, H., Okamoto, T., Hara, Y., Komine, O., Tamada, H., Maeda, M., Osako, F., Kobayashi, M., Nishiyama, A., Kataoka, Y., et al. (2020) · The EMBO Journal

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 179

P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways

Shiratori, M., Tozaki‐Saitoh, H., Yoshitake, M., Tsuda, M., & Inoue, K. (2010) · Journal of Neurochemistry

Adenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 153

Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT

Kataoka, A., Tozaki‐Saitoh, H., Koga, Y., Tsuda, M., & Inoue, K. (2009) · Journal of Neurochemistry

Adenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 121

Microglia and intractable chronic pain

Tsuda, M., Beggs, S., Salter, M. W., & Inoue, K. (2013) · Glia

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 113

Nociceptive signaling mediated by P2X3, P2X4 and P2X7 receptors

Inoue, K., & Tsuda, M. (2021) · Biochemical Pharmacology

Adenosine and Purinergic SignalingPain Mechanisms and Treatments

Cited by 78

A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior

Tashima, R., Koga, K., Yoshikawa, Y., Sekine, M., Watanabe, M., Tozaki-Saitoh, H., Furue, H., Yasaka, T., & Tsuda, M. (2021) · Proceedings of the National Academy of Sciences

Pain Mechanisms and TreatmentsPain Management and Treatment

Cited by 54

Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development

Tozaki‐Saitoh, H., Masuda, J., Kawada, R., Kojima, C., Yoneda, S., Masuda, T., Inoue, K., & Tsuda, M. (2019) · Glia

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 52

Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells

Ohgidani, M., Kato, T. A., Hosoi, M., Tsuda, M., Hayakawa, K., Hayaki, C., Iwaki, R., Sagata, N., Hashimoto, R., Inoue, K., et al. (2017) · Scientific Reports

Fibromyalgia and Chronic Fatigue Syndrome ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 49

Hypersusceptibility to DMCM-induced seizures during diazepam withdrawal in mice: evidence for upregulation of NMDA receptors

Tsuda, M., Shimizu, N., Yajima, Y., Suzuki, T., & Misawa, M. (1998) · Naunyn-Schmiedeberg's Archives of Pharmacology

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 33