Lennerz, Jochen K.

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

Cadwell, K., Liu, J. Y., Brown, S. L., Miyoshi, H., Loh, J., Lennerz, J. K., Kishi, C., Kc, W., Carrero, J. A., Hunt, S., et al. (2008) · Nature

Inflammatory Bowel DiseaseAutophagy in Disease and Therapy

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Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS–MAPK Reactivation

Tanaka, N., Lin, J. J., Li, C., Ryan, M. B., Zhang, J., Kiedrowski, L. A., Michel, A. G., Syed, M. U., Fella, K. A., Sakhi, M., et al. (2021) · Cancer Discovery

Protein Kinase Regulation and GTPase SignalingLung Cancer Treatments and Mutations

Cited by 527

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

Mitra, D., Luo, X., Morgan, A., Wang, J., Hoang, M. P., Lo, J., Guerrero, C. R., Lennerz, J. K., Mihm, M. C., Wargo, J. A., et al. (2012) · Nature

Melanoma and MAPK Pathwaysmelanin and skin pigmentation

Cited by 497

Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer

Yoda, S., Lin, J. J., Lawrence, M. S., Burke, B. J., Friboulet, L., Langenbucher, A., Dardaei, L., Prutisto-Chang, K., Dagogo-Jack, I., Timofeevski, S., et al. (2018) · Cancer Discovery

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 322

Clinical sensitivity and interpretation of PCR and serological COVID‐19 diagnostics for patients presenting to the hospital

Miller, T. E., Garcia Beltran, W. F., Bard, A. Z., Gogakos, T., Anahtar, M. N., Astudillo, M. G., Yang, D., Thierauf, J., Fisch, A. S., Mahowald, G. K., et al. (2020) · The FASEB Journal

SARS-CoV-2 detection and testingCOVID-19 Clinical Research Studies

Cited by 148

Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion–Positive Lung Cancer

Lin, J. J., Choudhury, N. J., Yoda, S., Zhu, V. W., Johnson, T. W., Sakhtemani, R., Dagogo-Jack, I., Digumarthy, S. R., Lee, C., Do, A., et al. (2021) · Clinical Cancer Research

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 145

Impact of BRAF Mutation Class on Disease Characteristics and Clinical Outcomes in BRAF-mutant Lung Cancer

Dagogo-Jack, I., Martinez, P., Yeap, B. Y., Ambrogio, C., Ferris, L. A., Lydon, C., Nguyen, T., Jessop, N. A., Iafrate, A. J., Johnson, B. E., et al. (2019) · Clinical Cancer Research

Lung Cancer Treatments and MutationsLung Cancer Diagnosis and Treatment

Cited by 130

Where is laboratory medicine headed in the next decade? Partnership model for efficient integration and adoption of artificial intelligence into medical laboratories

Carobene, A., Cabitza, F., Bernardini, S., Gopalan, R., Lennerz, J. K., Weir, C., & Cadamuro, J. (2023) · Clinical Chemistry and Laboratory Medicine (CCLM)

Artificial Intelligence in Healthcare and EducationClinical Laboratory Practices and Quality Control

Cited by 42

Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells

Capoccia, B. J., Lennerz, J. K. M., Bredemeyer, A. J., Klco, J. M., Frater, J. L., & Mills, J. C. (2011) · Physiological Genomics

Endoplasmic Reticulum Stress and DiseaseT-cell and B-cell Immunology

Cited by 33

Diagnostic Quality Model (DQM): an integrated framework for the assessment of diagnostic quality when using AI/ML

Lennerz, J. K., Salgado, R., Kim, G. E., Sirintrapun, S. J., Thierauf, J. C., Singh, A., Indave, I., Bard, A., Weissinger, S. E., Heher, Y. K., et al. (2023) · Clinical Chemistry and Laboratory Medicine (CCLM)

Artificial Intelligence in Healthcare and EducationClinical Laboratory Practices and Quality Control

Cited by 29

Laboratory-Developed Tests in the New European Union 2017/746 Regulation: Opportunities and Risks

Vogeser, M., Brüggemann, M., Lennerz, J., Stenzinger, A., & Gassner, U. M. (2021) · Clinical Chemistry

Healthcare RegulationClinical Laboratory Practices and Quality Control

Cited by 22

The impact of SOCS1 mutations in diffuse large B‐cell lymphoma

Mellert, K., Martin, M., Lennerz, J. K., Lüdeke, M., Staiger, A. M., Kreuz, M., Löffler, M., Schmitz, N., Trümper, L., Feller, A. C., et al. (2019) · British Journal of Haematology

Lymphoma Diagnosis and TreatmentCNS Lymphoma Diagnosis and Treatment

Cited by 17

Clinicopathologic characteristics and outcomes for patients with KRAS G12D-mutant NSCLC

Cooper, A. J., Muzikansky, A., Lennerz, J., Narinesingh, F., Mino-Kenudson, M., Hung, Y. P., Piotrowska, Z., Dagogo-Jack, I., Sequist, L. V., Gainor, J. F., et al. (2022) · JTO Clinical and Research Reports

Lung Cancer Treatments and MutationsLung Cancer Diagnosis and Treatment

Cited by 14