Kessenbrock, Kai

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

Kessenbrock, K., Plaks, V., & Werb, Z. (2010) · Cell

Protease and Inhibitor MechanismsTGF-β signaling in diseases

Cited by 5,151

Lifeact: a versatile marker to visualize F-actin

Riedl, J., Crevenna, A. H., Kessenbrock, K., Yu, J. H., Neukirchen, D., Bista, M., Bradke, F., Jenne, D., Holak, T. A., Werb, Z., et al. (2008) · Nature Methods

Cellular Mechanics and InteractionsAdvanced Fluorescence Microscopy Techniques

Cited by 2,189

Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps

Park, J., Wysocki, R. W., Amoozgar, Z., Maiorino, L., Fein, M. R., Jorns, J., Schott, A. F., Kinugasa-Katayama, Y., Lee, Y., Won, N. H., et al. (2016) · Science Translational Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmune cells in cancer

Cited by 984

Tumour heterogeneity and metastasis at single-cell resolution

Lawson, D. A., Kessenbrock, K., Davis, R. T., Pervolarakis, N., & Werb, Z. (2018) · Nature Cell Biology

Single-cell and spatial transcriptomicsCancer Genomics and Diagnostics

Cited by 606

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

Guerrero-Juarez, C. F., Dedhia, P. H., Jin, S., Ruiz-Vega, R., Ma, D., Liu, Y., Yamaga, K., Shestova, O., Gay, D. L., Yang, Z., et al. (2019) · Nature Communications

Wound Healing and TreatmentsPlanarian Biology and Electrostimulation

Cited by 521

Experimental Considerations for Single-Cell RNA Sequencing Approaches

Nguyen, Q. H., Pervolarakis, N., Nee, K., & Kessenbrock, K. (2018) · Frontiers in Cell and Developmental Biology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 170

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

Coulis, G., Jaime, D., Guerrero-Juarez, C., Kastenschmidt, J. M., Farahat, P. K., Nguyen, Q., Pervolarakis, N., McLinden, K., Thurlow, L., Movahedi, S., et al. (2023) · Science Advances

Muscle Physiology and DisordersCardiac Fibrosis and Remodeling

Cited by 150

An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy

Hachey, S. J., Movsesyan, S., Nguyen, Q. H., Burton-Sojo, G., Tankazyan, A., Wu, J., Hoang, T., Zhao, D., Wang, S., Hatch, M. M., et al. (2021) · Lab on a Chip

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 124

Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation

Mohammadi, M. R., Rodriguez, S. M., Luong, J. C., Li, S., Cao, R., Alshetaiwi, H., Lau, H., Davtyan, H., Jones, M. B., Jafari, M., et al. (2021) · Communications Biology

Pancreatic function and diabetesExtracellular vesicles in disease

Cited by 53

Targeting tumor–stromal interactions in triple-negative breast cancer using a human vascularized micro-tumor model

Hachey, S. J., Hatch, C. J., Gaebler, D., Mocherla, A., Nee, K., Kessenbrock, K., & Hughes, C. C. W. (2024) · Breast Cancer Research

Cancer Cells and MetastasisBreast Cancer Treatment Studies

Cited by 24