Jahnke, Wolfgang

Twenty years on: the impact of fragments on drug discovery

Erlanson, D. A., Fesik, S. W., Hubbard, R. E., Jahnke, W., & Jhoti, H. (2016) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsChemical Synthesis and Analysis

Cited by 1,000

Molecular basis of coiled-coil formation

Steinmetz, M. O., Jelesarov, I., Matousek, W. M., Honnappa, S., Jahnke, W., Missimer, J. H., Frank, S., Alexandrescu, A. T., & Kammerer, R. A. (2007) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 136

Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site

Fang, Z., Marshall, C. B., Nishikawa, T., Gossert, A. D., Jansen, J. M., Jahnke, W., & Ikura, M. (2018) · Cell Chemical Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 86

Intrinsically disordered regions in the transcription factor MYC:MAX modulate DNA binding via intramolecular interactions

Schütz, S., Bergsdorf, C., Hänni-Holzinger, S., Lingel, A., Renatus, M., Gossert, A. D., & Jahnke, W. (2023) · Biochemistry

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 9

Intrinsically Disordered Regions in the Transcription Factor MYC:MAX Modulate DNA Binding via Intramolecular Interactions

Schütz, S., Bergsdorf, C., Hänni-Holzinger, S., Lingel, A., Renatus, M., Gossert, A. D., & Jahnke, W. (2024) · Biochemistry

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 9