Isaacs, William B.

The repertoire of mutational signatures in human cancer

Alexandrov, L. B., Kim, J., Haradhvala, N. J., Huang, M. N., Tian Ng, A. W., Wu, Y., Boot, A., Covington, K. R., Gordenin, D. A., Bergstrom, E. N., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,496

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Aaltonen, L. A., Abascal, F., Abeshouse, A., Aburatani, H., Adams, D. J., Agrawal, N., Ahn, K. S., Ahn, S.-M., Aikata, H., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,064

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

Antonarakis, E. S., Lu, C., Wang, H., Luber, B., Nakazawa, M., Roeser, J. C., Chen, Y., Mohammad, T. A., Chen, Y., Fedor, H. L., et al. (2014) · New England Journal of Medicine

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 2,710

Mutations of the VHL tumour suppressor gene in renal carcinoma

Gnarra, J. R., Tory, K., Weng, Y., Schmidt, L., Wei, M. H., Li, H., Latif, F., Liu, S., Chen, F., Duh, F.-M., et al. (1994) · Nature Genetics

Renal cell carcinoma treatmentEar and Head Tumors

Cited by 1,730

Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer.

Hu, R., Dunn, T. A., Wei, S., Isharwal, S., Veltri, R. W., Humphreys, E., Han, M., Partin, A. W., Vessella, R. L., Isaacs, W. B., et al. (2009) · Cancer Research

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 1,077

The evolutionary history of 2,658 cancers

Gerstung, M., Jolly, C., Leshchiner, I., Dentro, S. C., Gonzalez, S., Rosebrock, D., Mitchell, T. J., Rubanova, Y., Anur, P., Yu, K., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 1,057

Patterns of somatic structural variation in human cancer genomes

Li, Y., Roberts, N. D., Wala, J. A., Shapira, O., Schumacher, S. E., Kumar, K., Khurana, E., Waszak, S., Korbel, J. O., Haber, J. E., et al. (2020) · Nature

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 867

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Cortés-Ciriano, I., Lee, J. J.-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C.-Z., Pellman, D. S., et al. (2020) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 712

Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing

Sfanos, K. S., Bruno, T. C., Maris, C. H., Xu, L., Thoburn, C. J., DeMarzo, A. M., Meeker, A. K., Isaacs, W. B., & Drake, C. G. (2008) · Clinical Cancer Research

T-cell and B-cell ImmunologyProstate Cancer Treatment and Research

Cited by 427

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Tubio, J. M. C., Li, Y., Ju, Y. S., Martincorena, I., Cooke, S. L., Tojo, M., Gundem, G., Pipinikas, C. P., Zamora, J., Raine, K., et al. (2014) · Science

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 412

Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent

Rebbeck, T. R., Devesa, S. S., Chang, B.-L., Bunker, C. H., Cheng, I., Cooney, K., Eeles, R., Fernandez, P., Giri, V. N., Gueye, S. M., et al. (2013) · Prostate Cancer

Global Cancer Incidence and ScreeningProstate Cancer Diagnosis and Treatment

Cited by 273

Ligand-dependent inhibition of β-catenin/TCF signaling by androgen receptor

Chesire, D. R., & Isaacs, W. B. (2002) · Oncogene

Wnt/β-catenin signaling in development and cancerProstate Cancer Treatment and Research

Cited by 151

Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men

Jin, G., Sun, J., Kim, S.-T., Feng, J., Wang, Z., Tao, S., Chen, Z., Purcell, L., Smith, S., Isaacs, W. B., et al. (2012) · Human Molecular Genetics

Genetic Associations and EpidemiologyHormonal and reproductive studies

Cited by 83

Evaluation of PPP2R2A as a prostate cancer susceptibility gene: A comprehensive germline and somatic study

Cheng, Y., Liu, W., Kim, S.-T., Sun, J., Lu, L., Sun, J., Zheng, S. L., Isaacs, W. B., & Xu, J. (2011) · Cancer Genetics

Prostate Cancer Treatment and ResearchGenetic factors in colorectal cancer

Cited by 64

Leveraging population admixture to characterize the heritability of complex traits

Zaitlen, N., Pasaniuc, B., Sankararaman, S., Bhatia, G., Zhang, J., Gusev, A., Young, T., Tandon, A., Pollack, S., Vilhjálmsson, B. J., et al. (2014) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 63

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Gusev, A., Shi, H., Kichaev, G., Pomerantz, M., Li, F., Long, H. W., Ingles, S. A., Kittles, R. A., Strom, S. S., Rybicki, B. A., et al. (2016) · Nature Communications

Genetic Associations and EpidemiologyProstate Cancer Treatment and Research

Cited by 51