Ozerov, Ivan V.

AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor

Ren, F., Ding, X., Zheng, M., Korzinkin, M., Cai, X., Zhu, W., Mantsyzov, A., Aliper, A., Aladinskiy, V., Cao, Z., et al. (2023) · Chemical Science

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

Cited by 365

A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

Ren, F., Aliper, A., Chen, J., Zhao, H., Rao, S., Kuppe, C., Ozerov, I. V., Zhang, M., Witte, K., Kruse, C., et al. (2025) · Nature Biotechnology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisComputational Drug Discovery Methods

Cited by 348

AI-powered therapeutic target discovery

Pun, F. W., Ozerov, I. V., & Zhavoronkov, A. (2023) · Trends in Pharmacological Sciences

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

Cited by 341

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

Ravi, R., Noonan, K. A., Pham, V., Bedi, R., Zhavoronkov, A., Ozerov, I. V., Makarev, E., V. Artemov, A., Wysocki, P. T., Mehra, R., et al. (2018) · Nature Communications

Cancer Immunotherapy and BiomarkersTGF-β signaling in diseases

Cited by 325

Design of efficient computational workflows for in silico drug repurposing

Vanhaelen, Q., Mamoshina, P., Aliper, A. M., Artemov, A., Lezhnina, K., Ozerov, I., Labat, I., & Zhavoronkov, A. (2017) · Drug Discovery Today

Computational Drug Discovery Methodsvaccines and immunoinformatics approaches

Cited by 150

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Pun, F. W., Liu, B. H. M., Long, X., Leung, H. W., Leung, G. H. D., Mewborne, Q. T., Gao, J., Shneyderman, A., Ozerov, I. V., Wang, J., et al. (2022) · Frontiers in Aging Neuroscience

Amyotrophic Lateral Sclerosis ResearchComputational Drug Discovery Methods

Cited by 115

Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization

Cortese, F., Klokov, D., Osipov, A., Stefaniak, J., Moskalev, A., Schastnaya, J., Cantor, C., Aliper, A., Mamoshina, P., Ushakov, I., et al. (2018) · Oncotarget

Effects of Radiation ExposureSpaceflight effects on biology

Cited by 83

Changes in the number of double-strand DNA breaks in Chinese hamster V79 cells exposed to γ-radiation with different dose rates

Kotenko, K., Bushmanov, A., Ozerov, I., Guryev, D., Anchishkina, N., Smetanina, N., Arkhangelskaya, E., Vorobyeva, N., & Osipov, A. (2013) · International Journal of Molecular Sciences

Effects of Radiation ExposureDNA Repair Mechanisms

Cited by 34

A review of the biomedical innovations for healthy longevity

Moskalev, A., Anisimov, V., Aliper, A., Artemov, A., Asadullah, K., Belsky, D., Baranova, A., de Grey, A., Dixit, V. D., Debonneuil, E., et al. (2017) · Aging

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 22