High, Stephen

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

Young, A. R. J., Chan, E. Y. W., Hu, X. W., Köchl, R., Crawshaw, S. G., High, S., Hailey, D. W., Lippincott-Schwartz, J., & Tooze, S. A. (2006) · Journal of Cell Science

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 815

The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER

Hall, B. S., Hill, K., McKenna, M., Ogbechi, J., High, S., Willis, A. E., & Simmonds, R. E. (2014) · PLoS Pathogens

Mycobacterium research and diagnosisTuberculosis Research and Epidemiology

Cited by 162

Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

Zong, G., Hu, Z., O’Keefe, S., Tranter, D., Iannotti, M. J., Baron, L., Hall, B., Corfield, K., Paatero, A. O., Henderson, M. J., et al. (2019) · Journal of the American Chemical Society

Toxin Mechanisms and ImmunotoxinsCellular transport and secretion

Cited by 93

Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum

Gamayun, I., O'Keefe, S., Pick, T., Klein, M.-C., Nguyen, D., McKibbin, C., Piacenti, M., Williams, H. M., Flitsch, S. L., Whitehead, R. C., et al. (2019) · Cell Chemical Biology

Ion Channels and ReceptorsCellular transport and secretion

Cited by 51

Posttranslational insertion of small membrane proteins by the bacterial signal recognition particle.

Steinberg, R., Origi, A., Natriashvili, A., Sarmah, P., Licheva, M., Walker, P. M., Kraft, C., High, S., Luirink, J., Shi, W. Q., et al. (2020) · PLOS Biology

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 34

Co-translational biogenesis of lipid droplet integral membrane proteins

Leznicki, P., Schneider, H. O., Harvey, J. V., Shi, W. Q., & High, S. (2022) · Journal of Cell Science

Lipid metabolism and biosynthesisCellular transport and secretion

Cited by 20

Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting

Tirincsi, A., O’Keefe, S., Nguyen, D., Sicking, M., Dudek, J., Förster, F., Jung, M., Hadzibeganovic, D., Helms, V., High, S., et al. (2022) · Cells

Cellular transport and secretionEndoplasmic Reticulum Stress and Disease

Cited by 20

Eeyarestatin 24 impairs SecYEG-dependent protein trafficking and inhibits growth of clinically relevant pathogens.

Steenhuis, M., Koningstein, G. M., Oswald, J., Pick, T., O’Keefe, S., Koch, H., Cavalié, A., Whitehead, R. C., Swanton, E., High, S., et al. (2021) · Molecular Microbiology

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 11

Proteomics identifies substrates and a novel component in hSnd2-dependent ER protein targeting

Tirincsi, A., O’Keefe, S., Nguyen, D., Sicking, M., Dudek, J., Förster, F., Jung, M., Hadzibeganovic, D., Helms, V., High, S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Cellular transport and secretionEndoplasmic Reticulum Stress and Disease

Cited by 7