Kooij, Gijs

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase and PKB signaling

Schreibelt, G., Kooij, G., Reijerkerk, A., van Doorn, R., Gringhuis, S. I., van der Pol, S., Weksler, B. B., Romero, I. A., Couraud, P., Piontek, J., et al. (2007) · The FASEB Journal

Barrier Structure and Function StudiesCell Adhesion Molecules Research

Cited by 347

Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke

Lopes Pinheiro, M. A., Kooij, G., Mizee, M. R., Kamermans, A., Enzmann, G., Lyck, R., Schwaninger, M., Engelhardt, B., & de Vries, H. E. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 247

Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis

Seijkens, T. T. P., van Tiel, C. M., Kusters, P. J. H., Atzler, D., Soehnlein, O., Zarzycka, B., Aarts, S. A. B. M., Lameijer, M., Gijbels, M. J., Beckers, L., et al. (2018) · Journal of the American College of Cardiology

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 195

Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

van Wageningen, T. A., Vlaar, E., Kooij, G., Jongenelen, C. A. M., Geurts, J. J. G., & van Dam, A.-M. (2019) · Acta Neuropathologica Communications

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 147

MicroRNAs Regulate Human Brain Endothelial Cell-Barrier Function in Inflammation: Implications for Multiple Sclerosis

Reijerkerk, A., Lopez-Ramirez, M. A., van het Hof, B., Drexhage, J. A. R., Kamphuis, W. W., Kooij, G., Vos, J. B., van der Pouw Kraan, T. C. T. M., van Zonneveld, A. J., Horrevoets, A. J., et al. (2013) · The Journal of Neuroscience

Barrier Structure and Function StudiesMicroRNA in disease regulation

Cited by 138

GM‐CSF promotes migration of human monocytes across the blood brain barrier

Vogel, D. Y. S., Kooij, G., Heijnen, P. D. A. M., Breur, M., Peferoen, L. A. N., van der Valk, P., de Vries, H. E., Amor, S., & Dijkstra, C. D. (2015) · European Journal of Immunology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 94

Adenosine triphosphate-binding cassette transporters mediate chemokine (C-C motif) ligand 2 secretion from reactive astrocytes: relevance to multiple sclerosis pathogenesis

Kooij, G., Mizee, M. R., van Horssen, J., Reijerkerk, A., Witte, M. E., Drexhage, J. A. R., van der Pol, S. M. A., van het Hof, B., Scheffer, G., Scheper, R., et al. (2011) · Brain

Drug Transport and Resistance MechanismsMultiple Sclerosis Research Studies

Cited by 90

The whipworm ( Trichuris suis ) secretes prostaglandin E2 to suppress proinflammatory properties in human dendritic cells

Laan, L. C., Williams, A. R., Stavenhagen, K., Giera, M., Kooij, G., Vlasakov, I., Kalay, H., Kringel, H., Nejsum, P., Thamsborg, S. M., et al. (2017) · The FASEB Journal

Parasites and Host InteractionsParasitic Diseases Research and Treatment

Cited by 63

ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy

Carrano, A., Snkhchyan, H., Kooij, G., van der Pol, S., van Horssen, J., Veerhuis, R., Hoozemans, J., Rozemuller, A., & de Vries, H. E. (2014) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDrug Transport and Resistance Mechanisms

Cited by 51

Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?

Broos, J. Y., van der Burgt, R. T. M., Konings, J., Rijnsburger, M., Werz, O., de Vries, H. E., Giera, M., & Kooij, G. (2024) · Journal of Neuroinflammation

Multiple Sclerosis Research StudiesFatty Acid Research and Health

Cited by 41

Association of Arachidonic Acid–Derived Lipid Mediators With Disease Severity in Patients With Relapsing and Progressive Multiple Sclerosis

Broos, J. Y., Loonstra, F. C., de Ruiter, L. R. J., Gouda, M., Fung, W. H., Schoonheim, M. M., Heijink, M., Strijbis, E. M. M., Teunissen, C., Killestein, J., et al. (2023) · Neurology

Multiple Sclerosis Research StudiesFatty Acid Research and Health

Cited by 29

Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction

Hansen, C. E., Vacondio, D., van der Molen, L., Jüttner, A. A., Fung, W. K., Karsten, M., van het Hof, B., Fontijn, R. D., Kooij, G., Witte, M. E., et al. (2025) · Cell Death & Disease

Barrier Structure and Function StudiesCerebrovascular and genetic disorders

Cited by 27