Agrawal, Sudhir

Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies

Agrawal, S., Jiang, Z., Zhao, Q., Shaw, D., Cai, Q., Roskey, A., Channavajjala, L., Saxinger, C., & Zhang, R. (1997) · Proceedings of the National Academy of Sciences

DNA and Nucleic Acid ChemistryRNA Interference and Gene Delivery

Cited by 226

Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis

LaCasse, E. C., Cherton-Horvat, G. G., Hewitt, K. E., Jerome, L. J., Morris, S. J., Kandimalla, E. R., Yu, D., Wang, H., Wang, W., Zhang, R., et al. (2006) · Clinical Cancer Research

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 128

Novel Toll-Like Receptor 9 Agonist Induces Epidermal Growth Factor Receptor (EGFR) Inhibition and Synergistic Antitumor Activity with EGFR Inhibitors

Damiano, V., Caputo, R., Bianco, R., D'Armiento, F. P., Leonardi, A., De Placido, S., Bianco, A. R., Agrawal, S., Ciardiello, F., & Tortora, G. (2006) · Clinical Cancer Research

HER2/EGFR in Cancer ResearchImmune Response and Inflammation

Cited by 90

Experimental therapy of human prostate cancer by inhibiting MDM2 expression with novel mixed‐backbone antisense oligonucleotides: In vitro and in vivo activities and mechanisms

Wang, H., Yu, D., Agrawal, S., & Zhang, R. (2003) · The Prostate

Cancer-related Molecular PathwaysProstate Cancer Treatment and Research

Cited by 78

TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts

Damiano, V., Caputo, R., Garofalo, S., Bianco, R., Rosa, R., Merola, G., Gelardi, T., Racioppi, L., Fontanini, G., De Placido, S., et al. (2007) · Proceedings of the National Academy of Sciences

Angiogenesis and VEGF in CancerColorectal Cancer Treatments and Studies

Cited by 71

Toll-like Receptor 9 Agonist IMO Cooperates with Cetuximab in K - Ras Mutant Colorectal and Pancreatic Cancers

Rosa, R., Melisi, D., Damiano, V., Bianco, R., Garofalo, S., Gelardi, T., Agrawal, S., Di Nicolantonio, F., Scarpa, A., Bardelli, A., et al. (2011) · Clinical Cancer Research

Colorectal Cancer Treatments and StudiesProtein Kinase Regulation and GTPase Signaling

Cited by 54

Mixed-Backbone oligonucleotides as second-generation antisense agents with reduced phosphorothioate-related side effects

Zhou, W., & Agrawal, S. (1998) · Bioorganic & Medicinal Chemistry Letters

DNA and Nucleic Acid ChemistryRNA Interference and Gene Delivery

Cited by 41

Novel Oligonucleotides Containing Two 3′-Ends Complementary to Target mRNA Show Optimal Gene-Silencing Activity

Bhagat, L., Putta, M. R., Wang, D., Yu, D., Lan, T., Jiang, W., Sun, Z., Wang, H., Tang, J. X., La Monica, N., et al. (2011) · Journal of Medicinal Chemistry

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 20