Philipsen, Sjaak

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

Borg, J., Papadopoulos, P., Georgitsi, M., Gutiérrez, L., Grech, G., Fanis, P., Phylactides, M., Verkerk, A. J. M. H., van der Spek, P. J., Scerri, C. A., et al. (2010) · Nature Genetics

Hemoglobinopathies and Related DisordersKruppel-like factors research

Cited by 371

The active spatial organization of the β-globin locus requires the transcription factor EKLF

Drissen, R., Palstra, R.-J., Gillemans, N., Splinter, E., Grosveld, F., Philipsen, S., & de Laat, W. (2004) · Genes & Development

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 352

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

Engelen, E., Akinci, U., Bryne, J. C., Hou, J., Gontan, C., Moen, M., Szumska, D., Kockx, C., van IJcken, W., Dekkers, D. H. W., et al. (2011) · Nature Genetics

Congenital Ear and Nasal AnomaliesDevelopmental Biology and Gene Regulation

Cited by 255

Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis

Libregts, S. F., Gutiérrez, L., de Bruin, A. M., Wensveen, F. M., Papadopoulos, P., van Ijcken, W., Özgür, Z., Philipsen, S., & Nolte, M. A. (2011) · Blood

Erythropoietin and Anemia TreatmentIron Metabolism and Disorders

Cited by 204

KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells

Norton, L. J., Funnell, A. P. W., Burdach, J., Wienert, B., Kurita, R., Nakamura, Y., Philipsen, S., Pearson, R. C. M., Quinlan, K. G. R., & Crossley, M. (2017) · Blood Advances

Hemoglobinopathies and Related DisordersKruppel-like factors research

Cited by 65

Evolution of hemoglobin loci and their regulatory elements

Philipsen, S., & Hardison, R. C. (2018) · Blood Cells, Molecules, and Diseases

Hemoglobin structure and functionGenomics and Chromatin Dynamics

Cited by 51