Falchook, Gerald S.

Abstract CT008: Long-term outcomes with sotorasib in pretreated KRASp.G12C-mutated NSCLC: 2-year analysis of CodeBreaK100

Dy, G. K., Govindan, R., Velcheti, V., Falchook, G. S., Italiano, A., Wolf, J., Sacher, A. G., Takahashi, T., Ramalingam, S. S., Dooms, C., et al. (2022) · Cancer Research

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

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Trial in progress: A phase Ib study of AMG 510, a specific and irreversible KRASG12C inhibitor, in combination with other anticancer therapies in patients with advanced solid tumors harboring KRAS p.G12C mutation (CodeBreak 101).

Fakih, M., Durm, G. A., Govindan, R., Falchook, G. S., Soman, N., Henary, H. A., & Hong, D. S. (2020) · Journal of Clinical Oncology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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TNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11 -Mutant Tumors to Anti–PD-1 Immunotherapy

Ahronian, L. G., Sahu, S., Zhang, M., Patel, A. S., Geng, K., Bhattacharya, R., Falchook, G. S., Goldman, J. W., Spira, A. I., Punekar, S. R., et al. (2025) · Cancer Research

Cancer Immunotherapy and BiomarkersHistone Deacetylase Inhibitors Research

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A Phase 1/2, open label dose-escalation and expansion trial of NKT2152, an orally administered HIF2α inhibitor, to investigate safety, PK, PD and clinical activity in patients with advanced ccRCC

Jonasch, E., Hauke, R., Falchook, G., Logan, T., Gordon, M., Hall, E., Schuch, B., Bilen, M. A., Naqash, A., Zakaharia, Y., et al. (2023) · The Oncologist

Renal cell carcinoma treatmentCancer, Hypoxia, and Metabolism

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First-in-human, phase 1, open-label, dose-escalation, dose-expansion study of ADCT-901 as monotherapy in patients with select advanced solid tumors.

Harvey, R. D., Falchook, G. S., Naqash, A. R., Kim, J. W., Dowlati, A., Le Bruchec, Y., Coudert, I., Ervin-Haynes, A. L., & Sommerhalder, D. (2022) · Journal of Clinical Oncology

Monoclonal and Polyclonal Antibodies ResearchSynthesis and pharmacology of benzodiazepine derivatives

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