Kane, John P.

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS.

Wurfel, M. M., Kunitake, S. T., Lichenstein, H., Kane, J. P., & Wright, S. D. (1994) · The Journal of experimental medicine

Immune Response and InflammationSepsis Diagnosis and Treatment

Cited by 442

Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque

Rapp, J. H., Lespine, A., Hamilton, R. L., Colyvas, N., Chaumeton, A. H., Tweedie-Hardman, J., Kotite, L., Kunitake, S. T., Havel, R. J., & Kane, J. P. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 340

Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.

Schneider, W. J., Kovanen, P. T., Brown, M. S., Goldstein, J. L., Utermann, G., Weber, W., Havel, R. J., Kotite, L., Kane, J. P., Innerarity, T. L., et al. (1981) · Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 310

Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial

Gouni-Berthold, I., Alexander, V. J., Yang, Q., Hurh, E., Steinhagen-Thiessen, E., Moriarty, P. M., Hughes, S. G., Gaudet, D., Hegele, R. A., O'Dea, L. S. L., et al. (2021) · The Lancet Diabetes & Endocrinology

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 232

Primary Dysbetalipoproteinemia: Predominance of a Specific Apoprotein Species in Triglyceride-Rich Lipoproteins

Havel, R. J., & Kane, J. P. (1973) · Proceedings of the National Academy of Sciences

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 231

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia.

Péterfy, M., Ben-Zeev, O., Mao, H. Z., Weissglas-Volkov, D., Aouizerat, B. E., Pullinger, C. R., Frost, P. H., Kane, J. P., Malloy, M. J., Reue, K., et al. (2007) · Nature Genetics

Lipid metabolism and disordersLipid metabolism and biosynthesis

Cited by 226

Severe hypertriglyceridemia is primarily polygenic

Dron, J. S., Wang, J., Cao, H., McIntyre, A. D., Iacocca, M. A., Menard, J. R., Movsesyan, I., Malloy, M. J., Pullinger, C. R., Kane, J. P., et al. (2019) · Journal of Clinical Lipidology

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 222

Regulated expression of apolipoprotein E by human retinal pigment epithelial cells

Ishida, B. Y., Bailey, K. R., Duncan, K. G., Chalkley, R. J., Burlingame, A. L., Kane, J. P., & Schwartz, D. M. (2004) · Journal of Lipid Research

Retinal Diseases and TreatmentsCholesterol and Lipid Metabolism

Cited by 111

Remnants of lipoproteins of intestinal and hepatic origin in familial dysbetalipoproteinemia.

Kane, J. P., Chen, G. C., Hamilton, R. L., Hardman, D. A., Malloy, M. J., & Havel, R. J. (1983) · Arteriosclerosis: An Official Journal of the American Heart Association, Inc.

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 106

Effects of the Absence of Apolipoprotein E on Lipoproteins, Neurocognitive Function, and Retinal Function

Mak, A. C. Y., Pullinger, C. R., Tang, L. F., Wong, J. S., Deo, R. C., Schwarz, J.-M., Gugliucci, A., Movsesyan, I., Ishida, B. Y., Chu, C., et al. (2014) · JAMA Neurology

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 94

Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3.

Havel, R. J., Kotite, L., Kane, J. P., Tun, P., & Bersot, T. (1983) · Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 88

Relation of Increased Prebeta-1 High-Density Lipoprotein Levels to Risk of Coronary Heart Disease

Guey, L. T., Pullinger, C. R., Ishida, B. Y., O'Connor, P. M., Zellner, C., Francone, O. L., Laramie, J. M., Naya-Vigne, J. M., Siradze, K. A., Deedwania, P., et al. (2011) · The American Journal of Cardiology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 70

Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in patients with familial dysbetalipoproteinemia.

Stalenhoef, A. F., Malloy, M. J., Kane, J. P., & Havel, R. J. (1986) · Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 70

Mechanisms of statin-induced myalgia assessed by physiogenomic associations

Ruaño, G., Windemuth, A., Wu, A. H. B., Kane, J. P., Malloy, M. J., Pullinger, C. R., Kocherla, M., Bogaard, K., Gordon, B. R., Holford, T. R., et al. (2011) · Atherosclerosis

Pharmacogenetics and Drug MetabolismLipoproteins and Cardiovascular Health

Cited by 66

Biochemical Analysis of the Lipoprotein Lipase Truncation Variant, LPLS447X, Reveals Increased Lipoprotein Uptake

Hayne, C. K., Lafferty, M. J., Eglinger, B. J., Kane, J. P., & Neher, S. B. (2017) · Biochemistry

Lipid metabolism and disordersLipid metabolism and biosynthesis

Cited by 25

Structural variation across 138,134 samples in the TOPMed consortium

Jun, G., English, A., Metcalf, G., Yang, J., Chaisson, M., Pankratz, N., Menon, V., Salerno, W., Krasheninina, O., Smith, A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology

Cited by 24