Lalaoui, Najoua

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

Murphy, J. M., Czabotar, P. E., Hildebrand, J. M., Lucet, I. S., Zhang, J.-G., Alvarez-Diaz, S., Lewis, R., Lalaoui, N., Metcalf, D., Webb, A. I., et al. (2013) · Immunity

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 1,220

Tumor immune evasion arises through loss of TNF sensitivity

Kearney, C. J., Vervoort, S. J., Hogg, S. J., Ramsbottom, K. M., Freeman, A. J., Lalaoui, N., Pijpers, L., Michie, J., Brown, K. K., Knight, D. A., et al. (2018) · Science Immunology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 381

The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

Alvarez-Diaz, S., Dillon, C. P., Lalaoui, N., Tanzer, M. C., Rodriguez, D. A., Lin, A., Lebois, M., Hakem, R., Josefsson, E. C., O’Reilly, L. A., et al. (2016) · Immunity

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 242

PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF

Kearney, C. J., Lalaoui, N., Freeman, A. J., Ramsbottom, K. M., Silke, J., & Oliaro, J. (2017) · Cell Death & Differentiation

Cell death mechanisms and regulationCancer Immunotherapy and Biomarkers

Cited by 83

Targeting triple-negative breast cancers with the Smac-mimetic birinapant

Lalaoui, N., Merino, D., Giner, G., Vaillant, F., Chau, D., Liu, L., Kratina, T., Pal, B., Whittle, J. R., Etemadi, N., et al. (2020) · Cell Death & Differentiation

Cell death mechanisms and regulationHistone Deacetylase Inhibitors Research

Cited by 51