Gegg, Matthew E.

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

Gegg, M. E., Cooper, J. M., Chau, K.-Y., Rojo, M., Schapira, A. H. V., & Taanman, J.-W. (2010) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

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Mitochondrial and lysosomal biogenesis are activated following PINK 1/parkin‐mediated mitophagy

Ivankovic, D., Chau, K., Schapira, A. H. V., & Gegg, M. E. (2016) · Journal of Neurochemistry

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

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Silencing of PINK1 Expression Affects Mitochondrial DNA and Oxidative Phosphorylation in DOPAMINERGIC Cells

Gegg, M. E., Cooper, J. M., Schapira, A. H. V., & Taanman, J.-W. (2009) · PLoS ONE

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

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α-Synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells: an in vitro proof of concept study

Hurley, M. J., Menozzi, E., Koletsi, S., Bates, R., Gegg, M. E., Chau, K.-Y., Blottière, H. M., Macnaughtan, J., & Schapira, A. H. V. (2023) · Brain Communications

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Elevated cholesterol in APOE4 astrocytes drives mitochondrial cristae collapse and ATP synthase dysfunction

Lee, S., Munoz-Oreja, M., Villar-Fernandez, M., Goicoechea-Barrenechea, L., Fernandez-Pelayo, U., Perez-Rodriguez, D., Gegg, M., de Arbina, A. L., Spinazzola, A., & Holt, I. J. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

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