Uyar, Asli

Comprehensive evaluation of the 5xFAD mouse model for preclinical testing applications: A MODEL-AD study.

Oblak, A. L., Lin, P. B., Kotredes, K. P., Pandey, R. S., Garceau, D., Williams, H. M., Uyar, A., O’Rourke, R., O’Rourke, S., Ingraham, C., et al. (2021) · Frontiers in Aging Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 325

The chromatin accessibility signature of human immune aging stems from CD8+ T cells

Ucar, D., Márquez, E. J., Chung, C.-H., Marches, R., Rossi, R. J., Uyar, A., Wu, T.-C., George, J., Stitzel, M. L., Palucka, A. K., et al. (2017) · Journal of Experimental Medicine

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 200

Enhancing face validity of mouse models of Alzheimer’s disease with natural genetic variation

Onos, K. D., Uyar, A., Keezer, K. J., Jackson, H. M., Preuss, C., Acklin, C. J., O’Rourke, R., Buchanan, R., Cossette, T. L., Sukoff Rizzo, S. J., et al. (2019) · PLOS Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 93

Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H

Kotredes, K. P., Oblak, A., Pandey, R. S., Lin, P. B.-C., Garceau, D., Williams, H., Uyar, A., O’Rourke, R., O’Rourke, S., Ingraham, C., et al. (2021) · Frontiers in Aging Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 66

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

the MODEL-AD Consortium, Preuss, C., Pandey, R., Piazza, E., Fine, A., Uyar, A., Perumal, T., Garceau, D., Kotredes, K. P., Williams, H., et al. (2020) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease

Pandey, R. S., Graham, L., Uyar, A., Preuss, C., Howell, G. R., & Carter, G. W. (2019) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 37