Hildebrand, Peter W.

Crystal structure of opsin in its G-protein-interacting conformation

Scheerer, P., Park, J. H., Hildebrand, P. W., Kim, Y. J., Krauß, N., Choe, H.-W., Hofmann, K. P., & Ernst, O. P. (2008) · Nature

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 1,059

NGL Viewer: a web application for molecular visualization

Rose, A. S., & Hildebrand, P. W. (2015) · Nucleic Acids Research

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 462

A G protein-coupled receptor at work: the rhodopsin model

Hofmann, K. P., Scheerer, P., Hildebrand, P. W., Choe, H.-W., Park, J. H., Heck, M., & Ernst, O. P. (2009) · Trends in Biochemical Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 376

A Ligand Channel through the G Protein Coupled Receptor Opsin

Hildebrand, P. W., Scheerer, P., Park, J. H., Choe, H.-W., Piechnick, R., Ernst, O. P., Hofmann, K. P., & Heck, M. (2009) · PLoS ONE

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 124

Biasing AlphaFold2 to predict GPCRs and kinases with user-defined functional or structural properties

Sala, D., Hildebrand, P. W., & Meiler, J. (2023) · Frontiers in Molecular Biosciences

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 80

Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor

Batebi, H., Pérez-Hernández, G., Rahman, S. N., Lan, B., Kamprad, A., Shi, M., Speck, D., Tiemann, J. K. S., Guixà-González, R., Reinhardt, F., et al. (2024) · Nature Structural & Molecular Biology

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 38

mdciao: Accessible Analysis and Visualization of Molecular Dynamics Simulation Data

Pérez-Hernández, G., & Hildebrand, P. W. (2025) · PLOS Computational Biology

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 36

PSMC3 proteasome subunit variants are associated with neurodevelopmental delay and type I interferon production

Ebstein, F., Küry, S., Most, V., Rosenfelt, C., Scott-Boyer, M.-P., van Woerden, G. M., Besnard, T., Papendorf, J. J., Studencka-Turski, M., Wang, T., et al. (2023) · Science Translational Medicine

Genetics and Neurodevelopmental DisordersUbiquitin and proteasome pathways

Cited by 36

MutationExplorer : a webserver for mutation of proteins and 3D visualization of energetic impacts

Philipp, M., Moth, C. W., Ristic, N., Tiemann, J. K. S., Seufert, F., Panfilova, A., Meiler, J., Hildebrand, P. W., Stein, A., Wiegreffe, D., et al. (2024) · Nucleic Acids Research

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 35

Generic residue numbering of the GAIN domain of adhesion GPCRs

Seufert, F., Pérez-Hernández, G., Pándy-Szekeres, G., Guixà-González, R., Langenhan, T., Gloriam, D. E., & Hildebrand, P. W. (2025) · Nature Communications

Receptor Mechanisms and SignalingProtein Structure and Dynamics

Cited by 8

Unveiling the crucial neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

Küry, S., Stanton, J. E., van Woerden, G., Hsieh, T.-C., Rosenfelt, C., Scott-Boyer, M. P., Most, V., Wang, T., Papendorf, J. J., de Konink, C., et al. (2024) · medRxiv

Genetics and Neurodevelopmental DisordersUbiquitin and proteasome pathways

Cited by 6

Investigating the neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

Küry, S., Stanton, J. E., van Woerden, G. M., Bosc-Rosati, A., Hsieh, T.-C., Bray, L., Oloudé, M., Rosenfelt, C., Scott-Boyer, M. P., Most, V., et al. (2025) · Nature Communications

Ubiquitin and proteasome pathwaysGenetics and Neurodevelopmental Disorders

Cited by 3

Generic residue numbering of the GAIN domain of adhesion GPCRs

Seufert, F., Pérez-Hernández, G., Pándy-Szekeres, G., Guixà-González, R., Langenhan, T., Gloriam, D. E., & Hildebrand, P. W. (2024) · Research Square

Receptor Mechanisms and SignalingProtein Structure and Dynamics

Cited by 0