NGL Viewer: a web application for molecular visualization
Open accessAbstract
The NGL Viewer (http://proteinformatics.charite.de/ngl) is a web application for the visualization of macromolecular structures. By fully adopting capabilities of modern web browsers, such as WebGL, for molecular graphics, the viewer can interactively display large molecular complexes and is also unaffected by the retirement of third-party plug-ins like Flash and Java Applets. Generally, the web application offers comprehensive molecular visualization through a graphical user interface so that life scientists can easily access and profit from available structural data. It supports common structural file-formats (e.g. PDB, mmCIF) and a variety of molecular representations (e.g. 'cartoon, spacefill, licorice'). Moreover, the viewer can be embedded in other web sites to provide specialized visualizations of entries in structural databases or results of structure-related calculations.
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The 3D visualization employs NGL Viewer and is highly interactive, allowing users to drag, zoom, pan and spin the structure to thoroughly examine it.
“This 3D visualization, employing NGL Viewer (34,35), is highly interactive, allowing users to drag, zoom, pan and spin the structure to thoroughly examine it.”
From TCRD and pharos 2021: mining the human proteome for disease biology (2021) · cites this paper as [35]
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Cites
SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
Biasini, M., Bienert, S., Waterhouse, A. M., Arnold, K., Studer, G., Schmidt, T., Kiefer, F., Cassarino, T. G., Bertoni, M., Bordoli, L., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku340 · Cited by 4,621 · see citing works
Ashkenazy, H., Erez, E., Martz, E., Pupko, T., & Ben‐Tal, N. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq399 · Cited by 1,822 · see citing works
The detection of DNA-binding proteins by protein blotting
Bowen, B. C., Steinberg, J. A., Laemmli, U. K., & Weintraub, H. M. (1980) · Nucleic Acids Research · doi:10.1093/nar/8.1.1 · Cited by 727 · see citing works
The RCSB Protein Data Bank: new resources for research and education
Rose, P. W., Bi, C., Bluhm, W. F., Christie, C. H., Dimitropoulos, D., Dutta, S., Green, R. K., Goodsell, D. S., Prlić, A., Quesada, M., et al. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1200 · Cited by 523 · see citing works
The RCSB Protein Data Bank: views of structural biology for basic and applied research and education
Rose, P. W., Prlić, A., Bi, C., Bluhm, W. F., Christie, C. H., Dutta, S., Green, R. K., Goodsell, D. S., Westbrook, J., Woo, J., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1214 · Cited by 519 · see citing works
Ambient Occlusion and Edge Cueing for Enhancing Real Time Molecular Visualization
Tarini, M., Cignoni, P., & Montani, C. (2006) · IEEE Transactions on Visualization and Computer Graphics · doi:10.1109/tvcg.2006.115 · Cited by 406 · see citing works
3Dmol.js: molecular visualization with WebGL
Rego, N. B., & Koes, D. R. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu829 · Cited by 367 · see citing works
PDBe: Protein Data Bank in Europe
Velankar, S. S., Best, C., Beuth, B., Boutselakis, C. H., Cobley, N., Silva, A. W. S. D., Dimitropoulos, D., Golovin, A., Hirshberg, M., John, M., et al. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp916 · Cited by 337 · see citing works
Jmol – a paradigm shift in crystallographic visualization
Hanson, R. M. (2010) · Journal of Applied Crystallography · doi:10.1107/s0021889810030256 · Cited by 336 · see citing works
Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T., & Sussman, J. L. (2013) · Israel Journal of Chemistry · doi:10.1002/ijch.201300024 · Cited by 260 · see citing works
Baspinar, A., Cukuroglu, E., Nussinov, R., Keskin, Ö., & Gürsoy, A. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku397 · Cited by 201 · see citing works
Visualization of macromolecular structures
O’Donoghue, S. I., Goodsell, D. S., Frangakis, A. S., Jossinet, F., Laskowski, R. A., Nilges, M., Saibil, H. R., Schafferhans, A., Wade, R. C., Westhof, É., et al. (2010) · Nature Methods · doi:10.1038/nmeth.1427 · Cited by 167 · see citing works
AstexViewerTM †: a visualisation aid for structure-based drug design
Hartshorn, M. J. (2002) · Journal of Computer-Aided Molecular Design · doi:10.1023/a:1023813504011 · Cited by 145 · see citing works
PDBe: Protein Data Bank in Europe
Gutmanas, A., Alhroub, Y., Battle, G. M., Berrisford, J. M., Bochet, E., Conroy, M. J., Dana, J. M., Montecelo, M. A. F., van Ginkel, G., Gore, S. P., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1180 · Cited by 142 · see citing works
Bendix: intuitive helix geometry analysis and abstraction
Dahl, A. C. E., Chavent, M. G., & Sansom, M. S. P. (2012) · Bioinformatics · doi:10.1093/bioinformatics/bts357 · Cited by 131 · see citing works
GPU-based ray-casting of quadratic surfaces
Sigg, C., Weyrich, T., Botsch, M., et al. (2006) · UCL Discovery (University College London) · doi:10.5555/2386388.2386396 · Cited by 73 · see citing works
Chavent, M. G., Vanel, A., Tek, A., et al. (2011) · Journal of Computational Chemistry · doi:10.1002/jcc.21861 · Cited by 65 · see citing works
iview: an interactive WebGL visualizer for protein-ligand complex
Li, H., Leung, K., Nakane, T., et al. (2014) · BMC Bioinformatics · doi:10.1186/1471-2105-15-56 · Cited by 60 · see citing works
An Introduction to Biomolecular Graphics
Mura, C., McCrimmon, C. M., Vertrees, J., & Sawaya, M. R. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000918 · Cited by 60 · see citing works
GPU-powered tools boost molecular visualization
Chavent, M. G., Lévy, B., Krone, M., et al. (2011) · Briefings in Bioinformatics · doi:10.1093/bib/bbq089 · Cited by 42 · see citing works
Rose, A., Theune, D., Goede, A., & Hildebrand, P. W. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1062 · Cited by 10 · see citing works
Self-citationVoronoia4RNA—a database of atomic packing densities of RNA structures and their complexes
Ismer, J., Rose, A., Tiemann, J. K. S., et al. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1061 · Cited by 5 · see citing works
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Cited by
Sorted by citations
MolProbity: More and better reference data for improved all‐atom structure validation
Williams, C. J., Headd, J. J., Moriarty, N. W., Prisant, M. G., Videau, L. L., Deis, L. N., Verma, V., Keedy, D. A., Hintze, B. J., Chen, V. B., et al. (2018) · Protein Science · doi:10.1002/pro.3330 · Cited by 4,599 · see citing works
The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update
Afgan, E., Baker, D., Batut, B., van den Beek, M., Bouvier, D., Čech, M., Chilton, J., Clements, D., Coraor, N., Grüning, B. A., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky379 · Cited by 3,662 · see citing works
NGL viewer: web-based molecular graphics for large complexes
Rose, A. S., Bradley, A. R., Valasatava, Y., Duarte, J. M., Prlić, A., & Rose, P. W. (2018) · Bioinformatics · doi:10.1093/bioinformatics/bty419 · Cited by 489 · see citing works
Self-citationBERTology Meets Biology: Interpreting Attention in Protein Language Models
Vig, J., Madani, A., Varshney, L. R., Xiong, C., Socher, R., & Rajani, N. F. (2020) · doi:10.1101/2020.06.26.174417 · Cited by 338 · see citing works
TCRD and pharos 2021: mining the human proteome for disease biology
Sheils, T. K., Mathias, S. L., Kelleher, K. J., Siramshetty, V. B., Nguyen, D.-T., Bologa, C. G., Jensen, L. J., Vidović, D., Koleti, A., Schürer, S. C., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkaa993 · Cited by 160 · see citing works
Kriebel, K., Hieke, C., Müller-Hilke, B., Nakata, M., & Kreikemeyer, B. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00053 · Cited by 118 · see citing works
SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots
Moreira, I. S., Koukos, P. I., Melo, R., Almeida, J. G., Preto, A. J., Schaarschmidt, J., Trellet, M., Gümüş, Z. H., Costa, J., & Bonvin, A. M. J. J. (2017) · Scientific Reports · doi:10.1038/s41598-017-08321-2 · Cited by 98 · see citing works
Structural motif search across the protein universe with Folddisco
Kim, H., Kim, R. S., Mirdita, M., Yoon, J., & Steinegger, M. (2026) · Nature Biotechnology · doi:10.1038/s41587-026-03162-9 · Cited by 10 · see citing works
- Authors
- Rose, A. S., & Hildebrand, P. W.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- Corresponding author
- Rose, Alexander S.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-04-29
- Volume
- 43
- Issue
- W1
- Pages
- W576-W579
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- PMC
- PMC4489237
- OpenAlex
- W2069152576
- Cited by
- 462
- References
- 22
- Citations by year
- 2026: 28 · 2025: 29 · 2024: 34 · 2023: 35 · 2022: 40 · 2021: 32 · 2020: 67 · 2019: 57 · 2018: 80 · 2017: 45 · 2016: 14 · 2015: 1
- FWCI
- 18.94
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Nucleic Acids Research (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft (BI 893/8, HI 1502)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Enzyme Structure and Function
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
- Physical Sciences › Computer Science › Computer Graphics and Computer-Aided Design › Computer Graphics and Visualization Techniques
- Keywords
- NGL viewer, molecular visualization, macromolecular structure, WebGL, web-based visualization, Protein Data Bank, mmCIF, molecular representation, structural database
- MeSH terms
- Computer Graphics, Models, Molecular, Protein Conformation, Software, Internet, Macromolecular Substances
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