Mercurio, Frank

Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation

Sakamoto, K. M., Kim, K. B., Kumagai, A., Mercurio, F., Crews, C. M., & Deshaies, R. J. (2001) · Proceedings of the National Academy of Sciences

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 2,609

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

Didonato, J., Mercurio, F., Rosette, C., Wu-Li, J., Suyang, H., Ghosh, S., & Karin, M. (1996) · Molecular and Cellular Biology

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 707

Phosphorylation of IκBα Precedes but Is Not Sufficient for Its Dissociation from NF-κB

DiDonato, J. A., Mercurio, F., & Karin, M. (1995) · Molecular and Cellular Biology

NF-κB Signaling PathwaysSignaling Pathways in Disease

Cited by 337

Suprafacial Orientation of the SCFCdc4 Dimer Accommodates Multiple Geometries for Substrate Ubiquitination

Tang, X., Orlicky, S., Lin, Z., Willems, A., Neculai, D., Ceccarelli, D., Mercurio, F., Shilton, B. H., Sicheri, F., & Tyers, M. (2007) · Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 209