Shlomi, Tomer

Quantitative flux analysis reveals folate-dependent NADPH production

Fan, J., Ye, J., Kamphorst, J. J., Shlomi, T., Thompson, C. B., & Rabinowitz, J. D. (2014) · Nature

Folate and B Vitamins ResearchCancer, Hypoxia, and Metabolism

Cited by 1,114

Network-based prediction of human tissue-specific metabolism

Shlomi, T., Cabili, M. N., Herrgård, M. J., Palsson, B. Ø., & Ruppin, E. (2008) · Nature Biotechnology

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 637

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence

Kaplon, J., Zheng, L., Meissl, K., Chaneton, B., Selivanov, V. A., Mackay, G., van der Burg, S. H., Verdegaal, E. M. E., Cascante, M., Shlomi, T., et al. (2013) · Nature

Telomeres, Telomerase, and SenescenceCancer, Hypoxia, and Metabolism

Cited by 633

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

Frezza, C., Zheng, L., Folger, O., Rajagopalan, K. N., MacKenzie, E. D., Jerby, L., Micaroni, M., Chaneton, B., Adam, J., Hedley, A., et al. (2011) · Nature

Cancer, Hypoxia, and MetabolismHeme Oxygenase-1 and Carbon Monoxide

Cited by 503

Metabolite concentrations, fluxes and free energies imply efficient enzyme usage

Park, J. O., Rubin, S. A., Xu, Y.-F., Amador-Noguez, D., Fan, J., Shlomi, T., & Rabinowitz, J. D. (2016) · Nature Chemical Biology

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 453

Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia

Fan, J., Kamphorst, J. J., Mathew, R., Chung, M. K., White, E., Shlomi, T., & Rabinowitz, J. D. (2013) · Molecular Systems Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 428

Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro k cat measurements

Davidi, D., Noor, E., Liebermeister, W., Bar-Even, A., Flamholz, A., Tummler, K., Barenholz, U., Goldenfeld, M., Shlomi, T., & Milo, R. (2016) · Proceedings of the National Academy of Sciences

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 266

A genome‐scale computational study of the interplay between transcriptional regulation and metabolism

Shlomi, T., Eisenberg, Y., Sharan, R., & Ruppin, E. (2007) · Molecular Systems Biology

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 254

Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model

Yizhak, K., Benyamini, T., Liebermeister, W., Ruppin, E., & Shlomi, T. (2010) · Bioinformatics

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 253

Genome-Scale Metabolic Modeling Elucidates the Role of Proliferative Adaptation in Causing the Warburg Effect

Shlomi, T., Benyamini, T., Gottlieb, E., Sharan, R., & Ruppin, E. (2011) · PLoS Computational Biology

Cancer, Hypoxia, and MetabolismMicrobial Metabolic Engineering and Bioproduction

Cited by 244

Prediction of Microbial Growth Rate versus Biomass Yield by a Metabolic Network with Kinetic Parameters

Adadi, R., Volkmer, B., Milo, R., Heinemann, M., & Shlomi, T. (2012) · PLoS Computational Biology

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 179

Spatial-fluxomics provides a subcellular-compartmentalized view of reductive glutamine metabolism in cancer cells

Lee, W. D., Mukha, D., Aizenshtein, E., & Shlomi, T. (2019) · Nature Communications

Cancer, Hypoxia, and MetabolismMicrobial Metabolic Engineering and Bioproduction

Cited by 70

Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth

Mukha, D., Fokra, M., Feldman, A., Sarvin, B., Sarvin, N., Nevo-Dinur, K., Besser, E., Hallo, E., Aizenshtein, E., Schug, Z. T., et al. (2022) · Cell Metabolism

Cancer, Hypoxia, and MetabolismBiochemical Acid Research Studies

Cited by 69

Transcriptional regulation of protein complexes within and across species

Tan, K., Shlomi, T., Feizi, H., Ideker, T., & Sharan, R. (2007) · Proceedings of the National Academy of Sciences

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 58

Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro

Feldman, A., Mukha, D., Maor, I. I., Sedov, E., Koren, E., Yosefzon, Y., Shlomi, T., & Fuchs, Y. (2019) · Nature Communications

Hair Growth and DisordersAcne and Rosacea Treatments and Effects

Cited by 52