Dawson, Gerard R.

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype

McKernan, R. M., Rosahl, T. W., Reynolds, D. S., Sur, C., Wafford, K. A., Atack, J. R., Farrar, S., Myers, J., Cook, G., Ferris, P., et al. (2000) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

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Sedation and Anesthesia Mediated by Distinct GABA A Receptor Isoforms

Reynolds, D. S., Rosahl, T. W., Cirone, J., O'Meara, G. F., Haythornthwaite, A., Newman, R. J., Myers, J., Sur, C., Howell, O., Rutter, A. R., et al. (2003) · The Journal of Neuroscience

Anesthesia and Sedative AgentsNeuroscience and Neuropharmacology Research

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Evidence for a Significant Role of α3-Containing GABAAReceptors in Mediating the Anxiolytic Effects of Benzodiazepines

Dias, R., Sheppard, W. F. A., Fradley, R. L., Garrett, E. M., Stanley, J. L., Tye, S. J., Goodacre, S., Lincoln, R. J., Cook, S. M., Conley, R., et al. (2005) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 247

An Inverse Agonist Selective for α5 Subunit-Containing GABAA Receptors Enhances Cognition

Dawson, G. R., Maubach, K. A., Collinson, N., Cobain, M., Everitt, B. J., MacLeod, A. M., Choudhury, H. I., McDonald, L. M., Pillai, G., Rycroft, W., et al. (2006) · The Journal of Pharmacology and Experimental Therapeutics

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 241

Different GABA A receptor subtypes mediate the anxiolytic, abuse-related, and motor effects of benzodiazepine-like drugs in primates

Rowlett, J. K., Platt, D. M., Lelas, S., Atack, J. R., & Dawson, G. R. (2005) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 212

TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates

Atack, J. R., Wafford, K. A., Tye, S. J., Cook, S. M., Sohal, B., Pike, A., Sur, C., Melillo, D., Bristow, L., Bromidge, F., et al. (2006) · The Journal of Pharmacology and Experimental Therapeutics

Neuroscience and Neuropharmacology ResearchPharmacological Receptor Mechanisms and Effects

Cited by 188

Comparing the actions of lanicemine and ketamine in depression: key role of the anterior cingulate

Downey, D., Dutta, A., McKie, S., Dawson, G. R., Dourish, C. T., Craig, K., Smith, M. A., McCarthy, D. J., Harmer, C. J., Goodwin, G. M., et al. (2016) · European Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 116

Predicting treatment response to antidepressant medication using early changes in emotional processing

Browning, M., Kingslake, J., Dourish, C. T., Goodwin, G. M., Harmer, C. J., & Dawson, G. R. (2019) · European Neuropsychopharmacology

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 83

Agomelatine facilitates positive versus negative affective processing in healthy volunteer models

Harmer, C. J., de Bodinat, C., Dawson, G. R., Dourish, C. T., Waldenmaier, L., Adams, S., Cowen, P. J., & Goodwin, G. M. (2011) · Journal of Psychopharmacology

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

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Reducing Abuse Liability of GABAA/Benzodiazepine Ligands via Selective Partial Agonist Efficacy at α1 and α2/3 Subtypes

Ator, N. A., Atack, J. R., Hargreaves, R. J., Burns, H. D., & Dawson, G. R. (2010) · The Journal of Pharmacology and Experimental Therapeutics

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 66

All roads lead to glutamate: NMDA and AMPA receptors as targets for rapid-acting antidepressants

Freudenberg, F., Reif-Leonhard, C., Dawson, G. R., McKernan, R. M., & Reif, A. (2025) · Pharmacological Research

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

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RAT PHARMACOKINETICS AND PHARMACODYNAMICS OF A SUSTAINED RELEASE FORMULATION OF THE GABAA α5-SELECTIVE COMPOUND L-655,708

Atack, J. R., Pike, A., Clarke, A., Cook, S. M., Sohal, B., McKernan, R. M., & Dawson, G. R. (2006) · Drug Metabolism and Disposition

Neuroscience and Neuropharmacology ResearchPharmacogenetics and Drug Metabolism

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