Chance, Mark R.

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

Yang, J., Huang, J., Dasgupta, M., Sears, N., Miyagi, M., Wang, B., Chance, M. R., Chen, X., Du, Y., Wang, Y., et al. (2010) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsGenomics and Chromatin Dynamics

Cited by 340

Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors

Angel, T. E., Chance, M. R., & Palczewski, K. (2009) · Proceedings of the National Academy of Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 235

Structural waters define a functional channel mediating activation of the GPCR, rhodopsin

Angel, T. E., Gupta, S., Jastrzebska, B., Palczewski, K., & Chance, M. R. (2009) · Proceedings of the National Academy of Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 203

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Sangodkar, J., Perl, A., Tohme, R., Kiselar, J., Kastrinsky, D. B., Zaware, N., Izadmehr, S., Mazhar, S., Wiredja, D. D., O’Connor, C. M., et al. (2017) · Journal of Clinical Investigation

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 196

The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

Bulek, K., Liu, C., Swaidani, S., Wang, L., Page, R. C., Gulen, M. F., Herjan, T., Abbadi, A., Qian, W., Sun, D., et al. (2011) · Nature Immunology

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 192

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

Kiser, P. D., Golczak, M., Lodowski, D. T., Chance, M. R., & Palczewski, K. (2009) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 158

Conformational Dynamics of Activation for the Pentameric Complex of Dimeric G Protein-Coupled Receptor and Heterotrimeric G Protein

Orban, T., Jastrzebska, B., Gupta, S., Wang, B., Miyagi, M., Chance, M. R., & Palczewski, K. (2012) · Structure

Receptor Mechanisms and SignalingMass Spectrometry Techniques and Applications

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Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis

Kiser, P. D., Farquhar, E. R., Shi, W., Sui, X., Chance, M. R., & Palczewski, K. (2012) · Proceedings of the National Academy of Sciences

Enzyme Structure and FunctionPhotoreceptor and optogenetics research

Cited by 63

Visualizing Water Molecules in Transmembrane Proteins Using Radiolytic Labeling Methods

Orban, T., Gupta, S., Palczewski, K., & Chance, M. R. (2010) · Biochemistry

Receptor Mechanisms and SignalingProtein Structure and Dynamics

Cited by 45

Structural and functional basis of PU.1-BAF interaction enables targeting of lineage-specific transcription

Sadalge, D., Clasman, J. R., Topal, S., Musser, D., Von der Porten, L., Wu, S., Schultz, S. E., Austin, W., Huang, D., Gao, Y.-D., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

Chromatin Remodeling and CancerGenomics and Chromatin Dynamics

Cited by 2