Young, Neal S.

Mutations in TERT, the Gene for Telomerase Reverse Transcriptase, in Aplastic Anemia

Yamaguchi, H., Calado, R. T., Ly, H., Kajigaya, S., Baerlocher, G. M., Chanock, S. J., Lansdorp, P. M., & Young, N. S. (2005) · New England Journal of Medicine

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 723

Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

Yoshizato, T., Dumitriu, B., Hosokawa, K., Makishima, H., Yoshida, K., Townsley, D., Sato-Otsubo, A., Sato, Y., Liu, D., Suzuki, H., et al. (2015) · New England Journal of Medicine

Acute Myeloid Leukemia ResearchBlood disorders and treatments

Cited by 646

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia

Ley, T. J., DeSimone, J., Anagnou, N. P., Keller, G. H., Humphries, R. K., Turner, P. H., Young, N. S., Heller, P., & Nienhuis, A. W. (1982) · New England Journal of Medicine

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 490

Danazol Treatment for Telomere Diseases

Townsley, D. M., Dumitriu, B., Liu, D., Biancotto, A., Weinstein, B., Chen, C., Hardy, N., Mihalek, A. D., Lingala, S., Kim, Y. J., et al. (2016) · New England Journal of Medicine

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 415

Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo

Zoumbos, N. C., Gascon, P., Djeu, J. Y., & Young, N. S. (1985) · Proceedings of the National Academy of Sciences

Blood disorders and treatmentsinterferon and immune responses

Cited by 330

Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome

Yamaguchi, H., Baerlocher, G. M., Lansdorp, P. M., Chanock, S. J., Nunez, O., Sloand, E., & Young, N. S. (2003) · Blood

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 301

Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA

Fogarty, P. F., Yamaguchi, H., Wiestner, A., Baerlocher, G. M., Sloand, E., Zeng, W. S., Read, E. J., Lansdorp, P. M., & Young, N. S. (2003) · The Lancet

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 277

Telomere length in leukocyte subpopulations of patients with aplastic anemia

Brümmendorf, T. H., Maciejewski, J. P., Mak, J., Young, N. S., & Lansdorp, P. M. (2001) · Blood

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 233

Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia

Solomou, E. E., Rezvani, K., Mielke, S., Malide, D., Keyvanfar, K., Visconte, V., Kajigaya, S., Barrett, A. J., & Young, N. S. (2007) · Blood

T-cell and B-cell ImmunologyBlood disorders and treatments

Cited by 225

Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha.

Maciejewski, J. P., Selleri, C., Sato, T., Cho, H. J., Keefer, L. K., Nathan, C. F., & Young, N. S. (1995) · Journal of Clinical Investigation

Hematopoietic Stem Cell TransplantationNitric Oxide and Endothelin Effects

Cited by 209

Association of Telomere Length of Peripheral Blood Leukocytes With Hematopoietic Relapse, Malignant Transformation, and Survival in Severe Aplastic Anemia

Scheinberg, P., Cooper, J. N., Sloand, E. M., Wu, C. O., Calado, R. T., & Young, N. S. (2010) · JAMA

Telomeres, Telomerase, and SenescenceHematopoietic Stem Cell Transplantation

Cited by 205

Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia

Calado, R. T., Regal, J. A., Hills, M., Yewdell, W. T., Dalmazzo, L. F., Zago, M. A., Lansdorp, P. M., Hogge, D., Chanock, S. J., Estey, E. H., et al. (2009) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceAcute Myeloid Leukemia Research

Cited by 184

IFN-γ-mediated hematopoietic cell destruction in murine models of immune-mediated bone marrow failure

Chen, J., Feng, X., Desierto, M. J., Keyvanfar, K., & Young, N. S. (2015) · Blood

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 97

Deep sequencing and flow cytometric characterization of expanded effector memory CD8 + CD57 + T cells frequently reveals T-cell receptor Vβ oligoclonality and CDR3 homology in acquired aplastic anemia

Giudice, V., Feng, X., Lin, Z., Hu, W., Zhang, F., Qiao, W., Ibanez, M. D. P. F., Rios, O., & Young, N. S. (2018) · Haematologica

T-cell and B-cell ImmunologyBlood disorders and treatments

Cited by 92

Genetic variation in telomeric repeat binding factors 1 and 2 in aplastic anemia

Savage, S. A., Calado, R. T., Xin, Z.-T., Ly, H., Young, N. S., & Chanock, S. J. (2006) · Experimental Hematology

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 47

Aptamer-based proteomics of serum and plasma in acquired aplastic anemia

Giudice, V., Biancotto, A., Wu, Z., Cheung, F., Candia, J., Fantoni, G., Kajigaya, S., Rios, O., Townsley, D., Feng, X., et al. (2018) · Experimental Hematology

Hematological disorders and diagnosticsBlood disorders and treatments

Cited by 25

Telomere length recovery: a strong predictor of overall survival in acute promyelocytic leukemia

Baljevic, M., Dumitriu, B., Lee, J.-W., Paietta, E. M., Wiernik, P. H., Racevskis, J., Chen, C., Stein, E. M., Gallagher, R. E., Rowe, J. M., et al. (2016) · Acta Haematologica

Telomeres, Telomerase, and SenescenceRetinoids in leukemia and cellular processes

Cited by 20