Shi, Linyu

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

Yang, H., Wang, H., Shivalila, C. S., Cheng, A. W., Shi, L., & Jaenisch, R. (2013) · Cell

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 1,596

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

Zhou, H., Su, J., Hu, X., Zhou, C., Li, H., Chen, Z., Xiao, Q., Wang, B., Wu, W., Sun, Y., et al. (2020) · Cell

CRISPR and Genetic EngineeringRetinal Development and Disorders

Cited by 437

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

Geng, J., Ito, Y., Shi, L., Amin, P., Chu, J., Ouchida, A. T., Mookhtiar, A. K., Zhao, H., Xu, D., Shan, B., et al. (2017) · Nature Communications

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 325

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

Zhou, H., Liu, J., Zhou, C., Gao, N., Rao, Z., Li, H., Hu, X., Li, C., Yao, X., Shen, X., et al. (2018) · Nature Neuroscience

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 276

The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection

Buganim, Y., Markoulaki, S., van Wietmarschen, N., Hoke, H., Wu, T., Ganz, K., Akhtar-Zaidi, B., He, Y., Abraham, B. J., Porubsky, D., et al. (2014) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 163

CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration

Zhou, C., Hu, X., Tang, C., Liu, W., Wang, S., Zhou, Y., Zhao, Q., Bo, Q., Shi, L., Sun, X., et al. (2020) · National Science Review

CRISPR and Genetic EngineeringRetinal Diseases and Treatments

Cited by 69

Mini-dCas13X–mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy

Li, G., Jin, M., Li, Z., Xiao, Q., Lin, J., Yang, D., Liu, Y., Wang, X., Xie, L., Ying, W., et al. (2023) · Journal of Clinical Investigation

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 44