Pedicone, Chiara

Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis

Pedicone, C., Fernandes, S., Dungan, O. M., Dormann, S. M., Viernes, D. R., Adhikari, A. A., Choi, L. B., De Jong, E. P., Chisholm, J. D., & Kerr, W. G. (2020) · Journal of Cell Science

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 61

Targeting SHIP1 and SHIP2 in Cancer

Pedicone, C., Meyer, S. T., Chisholm, J. D., & Kerr, W. G. (2021) · Cancers

Protein Tyrosine PhosphatasesPI3K/AKT/mTOR signaling in cancer

Cited by 42

Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

Matera, A., Compagnion, A.-C., Pedicone, C., Kotah, J. M., Ivanov, A., Monsorno, K., Labouèbe, G., Leggio, L., Pereira-Iglesias, M., Beule, D., et al. (2025) · Immunity

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 34

Discovery of a novel SHIP1 agonist that promotes degradation of lipid-laden phagocytic cargo by microglia

Pedicone, C., Fernandes, S., Matera, A., Meyer, S. T., Loh, S., Ha, J.-H., Bernard, D., Chisholm, J. D., Paolicelli, R. C., & Kerr, W. G. (2022) · iScience

Neuroinflammation and Neurodegeneration MechanismsProtein Tyrosine Phosphatases

Cited by 26

SHIP inhibition mediates select TREM2-induced microglial functions

Ramakrishnan, G. S., Berry, W. L., Pacherille, A., Kerr, W. G., Chisholm, J. D., Pedicone, C., & Humphrey, M. B. (2024) · Molecular Immunology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 17